HCSGD entry for ABCA8
1. General information
| Official gene symbol | ABCA8 |
|---|---|
| Entrez ID | 10351 |
| Gene full name | ATP-binding cassette, sub-family A (ABC1), member 8 |
| Other gene symbols | |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0005524 | ATP binding | IEA | molecular_function |
| GO:0005743 | Mitochondrial inner membrane | IEA | cellular_component |
| GO:0005886 | Plasma membrane | TAS | cellular_component |
| GO:0006200 | ATP catabolic process | IDA | biological_process |
| GO:0006810 | Transport | IDA | biological_process |
| GO:0008152 | Metabolic process | IDA | biological_process |
| GO:0016021 | Integral component of membrane | IEA | cellular_component |
| GO:0042626 | ATPase activity, coupled to transmembrane movement of substances | IDA | molecular_function |
| GO:0055085 | Transmembrane transport | TAS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.0593197143 | 0.0197387561 | 0.5276593581 | 0.2735574658 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.3696331095 |
| GSE13712_SHEAR | Down | -0.7962709849 |
| GSE13712_STATIC | Down | -1.0210604850 |
| GSE19018 | Down | -0.2317060402 |
| GSE19899_A1 | Down | -0.2527665235 |
| GSE19899_A2 | Down | -1.2125832768 |
| PubMed_21979375_A1 | Down | -0.3889563724 |
| PubMed_21979375_A2 | Down | -0.4245839608 |
| GSE35957 | Up | 0.1304697793 |
| GSE36640 | Up | 0.4597546132 |
| GSE54402 | Down | -0.8979425199 |
| GSE9593 | Up | 0.0726225038 |
| GSE43922 | Down | -0.5575426508 |
| GSE24585 | Up | 1.7381957780 |
| GSE37065 | Down | -0.0049955178 |
| GSE28863_A1 | Up | 1.4031186657 |
| GSE28863_A2 | Up | 1.3091669742 |
| GSE28863_A3 | Up | 0.1883721814 |
| GSE28863_A4 | Down | -0.0785155571 |
| GSE48662 | Up | 0.2849550589 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-192-5p | MIMAT0000222 | MIRT004151 | Microarray | Functional MTI (Weak) | 16822819 |
| hsa-miR-335-5p | MIMAT0000765 | MIRT017399 | Microarray | Functional MTI (Weak) | 18185580 |
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