HCSGD entry for PKDREJ


1. General information

Official gene symbolPKDREJ
Entrez ID10343
Gene full namepolycystic kidney disease (polycystin) and REJ homolog (sperm receptor for egg jelly homolog, sea urchin)
Other gene symbols
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0005262Calcium channel activityIBAmolecular_function
GO:0005509Calcium ion bindingIEAmolecular_function
GO:0005886Plasma membraneIEAcellular_component
GO:0006812Cation transportIBAbiological_process
GO:0007218Neuropeptide signaling pathwayIEAbiological_process
GO:0007340Acrosome reactionTASbiological_process
GO:0016020MembraneTAScellular_component
GO:0016021Integral component of membraneIEAcellular_component
GO:0030001Metal ion transportIBAbiological_process
GO:0034220Ion transmembrane transportIBAbiological_process
GO:0050982Detection of mechanical stimulusIBAbiological_process
GO:0055085Transmembrane transportIBAbiological_process
GO:0060046Regulation of acrosome reactionIEAbiological_process
GO:0070588Calcium ion transmembrane transportIBAbiological_process
GO:0072511Divalent inorganic cation transportIBAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.55830964630.88697430190.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.1066140666
GSE13712_SHEARDown-0.0629066793
GSE13712_STATICUp0.2135301999
GSE19018Down-0.0716498141
GSE19899_A1Up0.0694476199
GSE19899_A2Down-0.0329510758
PubMed_21979375_A1Down-0.0624237645
PubMed_21979375_A2Down-0.1610100044
GSE35957Up0.1854525302
GSE36640Down-0.0422085513
GSE54402Up0.0157705151
GSE9593Up0.0927860703
GSE43922Up0.0712152179
GSE24585Up0.0629887128
GSE37065Up0.0543945241
GSE28863_A1Down-0.0272835110
GSE28863_A2Up0.0515247839
GSE28863_A3Up0.1073817286
GSE28863_A4Up0.1592689085
GSE48662Up0.0074168916

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase
No target information from mirTarBase
  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.