HCSGD entry for IKZF1

1. General information

Official gene symbolIKZF1
Entrez ID10320
Gene full nameIKAROS family zinc finger 1 (Ikaros)
Other gene symbolsHs.54452 IK1 IKAROS LYF1 PRO0758 ZNFN1A1 hIk-1
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0000122Negative regulation of transcription from RNA polymerase II promoterIEAbiological_process
GO:0001779Natural killer cell differentiationIEAbiological_process
GO:0003677DNA bindingTASmolecular_function
GO:0003700Sequence-specific DNA binding transcription factor activityIEAmolecular_function
GO:0005634NucleusIEAcellular_component
GO:0005721Centromeric heterochromatinIEAcellular_component
GO:0005737CytoplasmIEAcellular_component
GO:0006351Transcription, DNA-templatedIEAbiological_process
GO:0007049Cell cycleIEAbiological_process
GO:0007498Mesoderm developmentTASbiological_process
GO:0016568Chromatin modificationIEAbiological_process
GO:0030183B cell differentiationIEAbiological_process
GO:0030217T cell differentiationIEAbiological_process
GO:0030900Forebrain developmentIEAbiological_process
GO:0040018Positive regulation of multicellular organism growthIEAbiological_process
GO:0043565Sequence-specific DNA bindingIEAmolecular_function
GO:0045660Positive regulation of neutrophil differentiationIEAbiological_process
GO:0045944Positive regulation of transcription from RNA polymerase II promoterIEAbiological_process
GO:0046872Metal ion bindingIEAmolecular_function
GO:0046982Protein heterodimerization activityIEAmolecular_function
GO:0048535Lymph node developmentIEAbiological_process
GO:0048538Thymus developmentIEAbiological_process
GO:0048541Peyer's patch developmentIEAbiological_process
GO:0048732Gland developmentIEAbiological_process
GO:0051138Positive regulation of NK T cell differentiationIEAbiological_process
GO:0060041Retina development in camera-type eyeIEAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.84513083090.86252289050.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.0210383182
GSE13712_SHEARDown-0.0533101358
GSE13712_STATICUp0.0304558193
GSE19018Up0.0609098718
GSE19899_A1Up0.0370384867
GSE19899_A2Up0.0843199837
PubMed_21979375_A1Up0.0401764159
PubMed_21979375_A2Down-0.0157761121
GSE35957Up0.1225804263
GSE36640Down-0.0019338167
GSE54402Up0.0072469924
GSE9593Up0.0486707272
GSE43922Up0.0121952718
GSE24585Up0.1331236679
GSE37065Up0.0161281439
GSE28863_A1Down-0.1944866589
GSE28863_A2Down-0.1455941332
GSE28863_A3Up0.1413219247
GSE28863_A4Up0.1087564887
GSE48662Up0.0016583888

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-26b-5pMIMAT0000083MIRT029793MicroarrayFunctional MTI (Weak)19088304
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  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.