HCSGD entry for RTN3
1. General information
| Official gene symbol | RTN3 |
|---|---|
| Entrez ID | 10313 |
| Gene full name | reticulon 3 |
| Other gene symbols | ASYIP HAP NSPL2 NSPLII RTN3-A1 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0000139 | Golgi membrane | IEA | cellular_component |
| GO:0005615 | Extracellular space | TAS | cellular_component |
| GO:0005783 | Endoplasmic reticulum | IDA | cellular_component |
| GO:0005789 | Endoplasmic reticulum membrane | IEA | cellular_component |
| GO:0006915 | Apoptotic process | IEA | biological_process |
| GO:0006950 | Response to stress | IEA | biological_process |
| GO:0016021 | Integral component of membrane | IEA | cellular_component |
| GO:0016032 | Viral process | IEA | biological_process |
| GO:0016192 | Vesicle-mediated transport | IEA | biological_process |
| GO:0071786 | Endoplasmic reticulum tubular network organization | IMP | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.1603151362 | 0.5019934311 | 0.7942131941 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.0084845127 |
| GSE13712_SHEAR | Up | 0.1905306672 |
| GSE13712_STATIC | Down | -0.0838762348 |
| GSE19018 | Up | 0.5371723651 |
| GSE19899_A1 | Down | -0.0995773820 |
| GSE19899_A2 | Up | 0.0723758864 |
| PubMed_21979375_A1 | Down | -0.2367598434 |
| PubMed_21979375_A2 | Down | -0.4347833890 |
| GSE35957 | Up | 0.2424342944 |
| GSE36640 | Up | 0.6463723203 |
| GSE54402 | Down | -0.5840862130 |
| GSE9593 | Up | 0.4338944389 |
| GSE43922 | Down | -0.0200991253 |
| GSE24585 | Up | 0.4414871452 |
| GSE37065 | Up | 0.1264862526 |
| GSE28863_A1 | Up | 0.0424101663 |
| GSE28863_A2 | Down | -0.0440008192 |
| GSE28863_A3 | Down | -0.5696405562 |
| GSE28863_A4 | Up | 0.2334419282 |
| GSE48662 | Up | 0.2499791016 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-155-5p | MIMAT0000646 | MIRT020529 | Proteomics | Functional MTI (Weak) | 18668040 |
| hsa-miR-760 | MIMAT0004957 | MIRT036707 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-484 | MIMAT0002174 | MIRT041723 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-378a-3p | MIMAT0000732 | MIRT043942 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-106a-5p | MIMAT0000103 | MIRT048346 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-17-5p | MIMAT0000070 | MIRT050976 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: 1 abstracts the gene occurs.
PubMed ID of the article | Sentenece the gene occurs |
|---|---|
| 21784712 | Important findings included significant upregulation of p53 and several proapoptotic genes (including apoptosis-inducing factor, mitochondrion-associated 1, BCL2-like 11 [an apoptosis facilitator]; caspase 7 apoptosis-related cysteine peptidase; proteasome 26S subunit nonadenosine triphosphatase 10, programmed cell death 6, and reticulon 3) |
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