HCSGD entry for KATNB1
1. General information
| Official gene symbol | KATNB1 |
|---|---|
| Entrez ID | 10300 |
| Gene full name | katanin p80 (WD repeat containing) subunit B 1 |
| Other gene symbols | KAT |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0000922 | Spindle pole | IDA | cellular_component |
| GO:0005737 | Cytoplasm | IDA | cellular_component |
| GO:0005813 | Centrosome | IEA | cellular_component |
| GO:0005874 | Microtubule | IEA | cellular_component |
| GO:0005886 | Plasma membrane | IDA | cellular_component |
| GO:0006200 | ATP catabolic process | IDA | biological_process |
| GO:0006605 | Protein targeting | NAS | biological_process |
| GO:0007026 | Negative regulation of microtubule depolymerization | IMP | biological_process |
| GO:0007079 | Mitotic chromosome movement towards spindle pole | IEA | biological_process |
| GO:0008017 | Microtubule binding | IEA NAS | molecular_function |
| GO:0008152 | Metabolic process | IDA | biological_process |
| GO:0008352 | Katanin complex | IDA IEA TAS | cellular_component |
| GO:0008568 | Microtubule-severing ATPase activity | IDA | molecular_function |
| GO:0010942 | Positive regulation of cell death | IEA | biological_process |
| GO:0010976 | Positive regulation of neuron projection development | IEA | biological_process |
| GO:0015630 | Microtubule cytoskeleton | IDA | cellular_component |
| GO:0030424 | Axon | IEA | cellular_component |
| GO:0030426 | Growth cone | IEA | cellular_component |
| GO:0030496 | Midbody | IEA | cellular_component |
| GO:0031117 | Positive regulation of microtubule depolymerization | IMP | biological_process |
| GO:0043025 | Neuronal cell body | IEA | cellular_component |
| GO:0045502 | Dynein binding | IEA | molecular_function |
| GO:0046982 | Protein heterodimerization activity | IPI | molecular_function |
| GO:0051013 | Microtubule severing | IEA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.0818890126 | 0.8707852057 | 0.6034156495 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.1670995966 |
| GSE13712_SHEAR | Down | -0.1407285912 |
| GSE13712_STATIC | Down | -0.0621947177 |
| GSE19018 | Up | 0.3035842879 |
| GSE19899_A1 | Up | 0.1385505362 |
| GSE19899_A2 | Up | 0.5832291074 |
| PubMed_21979375_A1 | Up | 1.0254353511 |
| PubMed_21979375_A2 | Up | 1.1525323480 |
| GSE35957 | Down | -0.1078245995 |
| GSE36640 | Up | 0.2717444153 |
| GSE54402 | Up | 0.1447907078 |
| GSE9593 | Up | 0.0205659942 |
| GSE43922 | Up | 0.1866771689 |
| GSE24585 | Down | -0.6405687094 |
| GSE37065 | Down | -0.1156753934 |
| GSE28863_A1 | Down | -0.0678580313 |
| GSE28863_A2 | Up | 0.0736542640 |
| GSE28863_A3 | Up | 0.0926413605 |
| GSE28863_A4 | Up | 0.0115657326 |
| GSE48662 | Up | 0.2134585054 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-328-3p | MIMAT0000752 | MIRT043768 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-25-3p | MIMAT0000081 | MIRT050360 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-let-7e-5p | MIMAT0000066 | MIRT051547 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
