HCSGD entry for APC2
1. General information
| Official gene symbol | APC2 |
|---|---|
| Entrez ID | 10297 |
| Gene full name | adenomatosis polyposis coli 2 |
| Other gene symbols | APCL |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0000139 | Golgi membrane | IEA | cellular_component |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005737 | Cytoplasm | IDA | cellular_component |
| GO:0005794 | Golgi apparatus | IDA | cellular_component |
| GO:0005881 | Cytoplasmic microtubule | IDA IMP | cellular_component |
| GO:0005884 | Actin filament | IDA | cellular_component |
| GO:0008013 | Beta-catenin binding | IDA IEA | molecular_function |
| GO:0008017 | Microtubule binding | IEA | molecular_function |
| GO:0016055 | Wnt signaling pathway | IEA | biological_process |
| GO:0016342 | Catenin complex | IDA | cellular_component |
| GO:0030178 | Negative regulation of Wnt signaling pathway | IEA | biological_process |
| GO:0031258 | Lamellipodium membrane | IDA | cellular_component |
| GO:0035414 | Negative regulation of catenin import into nucleus | IDA | biological_process |
| GO:0048471 | Perinuclear region of cytoplasm | IDA | cellular_component |
| GO:0090090 | Negative regulation of canonical Wnt signaling pathway | IDA IEA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.3836763953 | 0.8551873029 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.0332735649 |
| GSE13712_SHEAR | Down | -0.1270698605 |
| GSE13712_STATIC | Up | 0.0186687741 |
| GSE19018 | Up | 0.0126838931 |
| GSE19899_A1 | Down | -0.0555703901 |
| GSE19899_A2 | Up | 0.2447041080 |
| PubMed_21979375_A1 | Down | -0.0185729313 |
| PubMed_21979375_A2 | Down | -0.1597314899 |
| GSE35957 | Up | 0.1447933521 |
| GSE36640 | Up | 0.1612116061 |
| GSE54402 | Down | -0.0508436798 |
| GSE9593 | Up | 0.0156252179 |
| GSE43922 | Up | 0.2242409558 |
| GSE24585 | Up | 0.2466834366 |
| GSE37065 | Up | 0.0423538027 |
| GSE28863_A1 | Down | -0.1014411944 |
| GSE28863_A2 | Down | -0.0420643739 |
| GSE28863_A3 | Up | 0.4489438637 |
| GSE28863_A4 | Up | 0.0905473258 |
| GSE48662 | Down | -0.2962028843 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
No target information from mirTarBase
- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
