HCSGD entry for BCKDK
1. General information
| Official gene symbol | BCKDK |
|---|---|
| Entrez ID | 10295 |
| Gene full name | branched chain ketoacid dehydrogenase kinase |
| Other gene symbols | BCKDKD BDK |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0004674 | Protein serine/threonine kinase activity | IEA ISS | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005524 | ATP binding | IEA ISS | molecular_function |
| GO:0005739 | Mitochondrion | TAS | cellular_component |
| GO:0005947 | Mitochondrial alpha-ketoglutarate dehydrogenase complex | IEA ISS TAS | cellular_component |
| GO:0009063 | Cellular amino acid catabolic process | NAS | biological_process |
| GO:0009083 | Branched-chain amino acid catabolic process | ISS TAS | biological_process |
| GO:0016301 | Kinase activity | IEA TAS | molecular_function |
| GO:0016310 | Phosphorylation | ISS TAS | biological_process |
| GO:0047323 | [3-methyl-2-oxobutanoate dehydrogenase (acetyl-transferring)] kinase activity | IEA | molecular_function |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.1711241632 | 0.2952871661 | 0.8136125542 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.6066059174 |
| GSE13712_SHEAR | Down | -0.1737235099 |
| GSE13712_STATIC | Down | -0.0845518631 |
| GSE19018 | Up | 0.3962617955 |
| GSE19899_A1 | Up | 0.2692168239 |
| GSE19899_A2 | Up | 0.3999085710 |
| PubMed_21979375_A1 | Up | 1.6143474358 |
| PubMed_21979375_A2 | Up | 0.5597018788 |
| GSE35957 | Down | -0.4188799061 |
| GSE36640 | Down | -0.0767647593 |
| GSE54402 | Up | 0.4555137603 |
| GSE9593 | Down | -0.3131072225 |
| GSE43922 | Up | 0.0160745789 |
| GSE24585 | Down | -0.2847484058 |
| GSE37065 | Down | -0.0184739171 |
| GSE28863_A1 | Up | 0.1459124945 |
| GSE28863_A2 | Up | 0.0120022742 |
| GSE28863_A3 | Down | -0.3938364654 |
| GSE28863_A4 | Down | -0.2213698534 |
| GSE48662 | Up | 0.1061432613 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Name | Drug | Accession number |
|---|---|---|
| Adenosine-5'-Diphosphate Monothiophosphate | DB01660 | EXPT02847 |
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-7-5p | MIMAT0000252 | MIRT025739 | Microarray | Functional MTI (Weak) | 19073608 |
| hsa-miR-103a-3p | MIMAT0000101 | MIRT027050 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-miR-615-3p | MIMAT0003283 | MIRT040213 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-92b-3p | MIMAT0003218 | MIRT040528 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-125b-5p | MIMAT0000423 | MIRT046097 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-10a-5p | MIMAT0000253 | MIRT047623 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
