HCSGD entry for RGS19
1. General information
| Official gene symbol | RGS19 |
|---|---|
| Entrez ID | 10287 |
| Gene full name | regulator of G-protein signaling 19 |
| Other gene symbols | GAIP RGSGAIP |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0001965 | G-protein alpha-subunit binding | IEA | molecular_function |
| GO:0005096 | GTPase activator activity | IBA | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005737 | Cytoplasm | IBA | cellular_component |
| GO:0005794 | Golgi apparatus | TAS | cellular_component |
| GO:0005834 | Heterotrimeric G-protein complex | TAS | cellular_component |
| GO:0005886 | Plasma membrane | IBA | cellular_component |
| GO:0005903 | Brush border | IEA | cellular_component |
| GO:0006914 | Autophagy | IEA | biological_process |
| GO:0007186 | G-protein coupled receptor signaling pathway | TAS | biological_process |
| GO:0007264 | Small GTPase mediated signal transduction | TAS | biological_process |
| GO:0016020 | Membrane | TAS | cellular_component |
| GO:0030136 | Clathrin-coated vesicle | IEA | cellular_component |
| GO:0038032 | Termination of G-protein coupled receptor signaling pathway | IEA | biological_process |
| GO:0043085 | Positive regulation of catalytic activity | IBA | biological_process |
| GO:0043547 | Positive regulation of GTPase activity | IBA | biological_process |
| GO:0050790 | Regulation of catalytic activity | IBA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.2591014513 | 0.5349070818 | 0.9524779221 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.1926516771 |
| GSE13712_SHEAR | Up | 0.1077457209 |
| GSE13712_STATIC | Down | -0.0293674406 |
| GSE19018 | Down | -0.2446729643 |
| GSE19899_A1 | Up | 0.2588449047 |
| GSE19899_A2 | Up | 0.9647973508 |
| PubMed_21979375_A1 | Up | 1.3633301680 |
| PubMed_21979375_A2 | Up | 0.3075214816 |
| GSE35957 | Down | -0.7565750280 |
| GSE36640 | Up | 0.2153797711 |
| GSE54402 | Up | 0.1762649120 |
| GSE9593 | Down | -0.0240998359 |
| GSE43922 | Up | 0.0831512755 |
| GSE24585 | Down | -0.0782856308 |
| GSE37065 | Down | -0.0898960368 |
| GSE28863_A1 | Down | -0.1903653538 |
| GSE28863_A2 | Down | -0.2257118351 |
| GSE28863_A3 | Up | 0.0644900170 |
| GSE28863_A4 | Down | -0.0446977850 |
| GSE48662 | Up | 0.0677326835 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-98-5p | MIMAT0000096 | MIRT027736 | Microarray | Functional MTI (Weak) | 19088304 |
| hsa-miR-125b-5p | MIMAT0000423 | MIRT045892 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
