HCSGD entry for NET1
1. General information
| Official gene symbol | NET1 |
|---|---|
| Entrez ID | 10276 |
| Gene full name | neuroepithelial cell transforming 1 |
| Other gene symbols | ARHGEF8 NET1A |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0001558 | Regulation of cell growth | NAS | biological_process |
| GO:0005085 | Guanyl-nucleotide exchange factor activity | TAS | molecular_function |
| GO:0005089 | Rho guanyl-nucleotide exchange factor activity | IEA | molecular_function |
| GO:0005634 | Nucleus | IEA | cellular_component |
| GO:0005829 | Cytosol | TAS | cellular_component |
| GO:0007165 | Signal transduction | TAS | biological_process |
| GO:0007264 | Small GTPase mediated signal transduction | TAS | biological_process |
| GO:0032321 | Positive regulation of Rho GTPase activity | IMP | biological_process |
| GO:0035556 | Intracellular signal transduction | IEA | biological_process |
| GO:0043065 | Positive regulation of apoptotic process | IDA TAS | biological_process |
| GO:0048011 | Neurotrophin TRK receptor signaling pathway | TAS | biological_process |
| GO:0051056 | Regulation of small GTPase mediated signal transduction | TAS | biological_process |
| GO:0070301 | Cellular response to hydrogen peroxide | IDA | biological_process |
| GO:0071479 | Cellular response to ionizing radiation | IDA | biological_process |
| GO:0097190 | Apoptotic signaling pathway | TAS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.9300105543 | 0.0025034877 | 0.9999902473 | 0.0986441617 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.2154649044 |
| GSE13712_SHEAR | Down | -0.6353821651 |
| GSE13712_STATIC | Down | -0.1281701679 |
| GSE19018 | Down | -0.6126101406 |
| GSE19899_A1 | Down | -0.4987426819 |
| GSE19899_A2 | Down | -1.0206498726 |
| PubMed_21979375_A1 | Down | -1.7077805813 |
| PubMed_21979375_A2 | Down | -1.3753294408 |
| GSE35957 | Down | -1.1491393871 |
| GSE36640 | Down | -0.7872840302 |
| GSE54402 | Up | 0.4006339936 |
| GSE9593 | Down | -0.2102348972 |
| GSE43922 | Down | -0.5210867704 |
| GSE24585 | Up | 0.3247929620 |
| GSE37065 | Up | 0.1489513723 |
| GSE28863_A1 | Down | -0.7786017540 |
| GSE28863_A2 | Up | 0.4078295751 |
| GSE28863_A3 | Down | -0.8391066069 |
| GSE28863_A4 | Up | 0.1664776847 |
| GSE48662 | Down | -0.4270390997 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-340-5p | MIMAT0004692 | MIRT019642 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-miR-26b-5p | MIMAT0000083 | MIRT029990 | Microarray | Functional MTI (Weak) | 19088304 |
| hsa-miR-24-3p | MIMAT0000080 | MIRT030610 | Microarray | Functional MTI (Weak) | 19748357 |
| hsa-miR-320a | MIMAT0000510 | MIRT044778 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
