HCSGD entry for AKAP8
1. General information
| Official gene symbol | AKAP8 |
|---|---|
| Entrez ID | 10270 |
| Gene full name | A kinase (PRKA) anchor protein 8 |
| Other gene symbols | AKAP 95 AKAP-8 AKAP-95 AKAP95 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0000793 | Condensed chromosome | IEA | cellular_component |
| GO:0001939 | Female pronucleus | IEA | cellular_component |
| GO:0003677 | DNA binding | IEA | molecular_function |
| GO:0003690 | Double-stranded DNA binding | IEA | molecular_function |
| GO:0005634 | Nucleus | IDA IEA | cellular_component |
| GO:0005730 | Nucleolus | IDA | cellular_component |
| GO:0005739 | Mitochondrion | IEA | cellular_component |
| GO:0005794 | Golgi apparatus | IEA | cellular_component |
| GO:0006810 | Transport | IEA | biological_process |
| GO:0007067 | Mitosis | TAS | biological_process |
| GO:0007076 | Mitotic chromosome condensation | IEA | biological_process |
| GO:0007165 | Signal transduction | TAS | biological_process |
| GO:0008270 | Zinc ion binding | IEA | molecular_function |
| GO:0016020 | Membrane | IEA | cellular_component |
| GO:0016363 | Nuclear matrix | ISS | cellular_component |
| GO:0034237 | Protein kinase A regulatory subunit binding | IEA | molecular_function |
Entries Per Page
Displaying Page of
4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.0386731507 | 0.8970427985 | 0.4442262402 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.2795825571 |
| GSE13712_SHEAR | Up | 0.3306114795 |
| GSE13712_STATIC | Up | 0.2772840680 |
| GSE19018 | Down | -0.4359359519 |
| GSE19899_A1 | Up | 0.1725979443 |
| GSE19899_A2 | Up | 0.7961478268 |
| PubMed_21979375_A1 | Up | 1.3202409703 |
| PubMed_21979375_A2 | Up | 1.2678162938 |
| GSE35957 | Down | -0.0659989347 |
| GSE36640 | Down | -0.3116529715 |
| GSE54402 | Up | 0.5105747136 |
| GSE9593 | Down | -0.2101575448 |
| GSE43922 | Up | 0.3782166505 |
| GSE24585 | Down | -0.2038798440 |
| GSE37065 | Down | -0.1299241483 |
| GSE28863_A1 | Up | 0.0959530246 |
| GSE28863_A2 | Down | -0.0669085592 |
| GSE28863_A3 | Up | 0.2069400954 |
| GSE28863_A4 | Up | 0.1599780109 |
| GSE48662 | Down | -0.2478279430 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-let-7b-5p | MIMAT0000063 | MIRT001654 | pSILAC//Proteomics;Other | Functional MTI (Weak) | 18668040 |
| hsa-miR-218-5p | MIMAT0000275 | MIRT024227 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-let-7d-5p | MIMAT0000065 | MIRT032126 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-miR-92b-3p | MIMAT0003218 | MIRT040654 | CLASH | Functional MTI (Weak) | 23622248 |
Entries Per Page
Displaying Page of
- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
