HCSGD entry for SF3B4
1. General information
| Official gene symbol | SF3B4 |
|---|---|
| Entrez ID | 10262 |
| Gene full name | splicing factor 3b, subunit 4, 49kDa |
| Other gene symbols | AFD1 Hsh49 SAP49 SF3b49 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0000166 | Nucleotide binding | IEA | molecular_function |
| GO:0000375 | RNA splicing, via transesterification reactions | TAS | biological_process |
| GO:0000398 | MRNA splicing, via spliceosome | IC TAS | biological_process |
| GO:0003676 | Nucleic acid binding | IEA | molecular_function |
| GO:0003723 | RNA binding | IEA | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005654 | Nucleoplasm | TAS | cellular_component |
| GO:0005681 | Spliceosomal complex | IDA | cellular_component |
| GO:0005689 | U12-type spliceosomal complex | IDA | cellular_component |
| GO:0006397 | MRNA processing | TAS | biological_process |
| GO:0008380 | RNA splicing | TAS | biological_process |
| GO:0010467 | Gene expression | TAS | biological_process |
Entries Per Page
Displaying Page of
4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.0778767942 | 0.7541516242 | 0.5887165375 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.2857303151 |
| GSE13712_SHEAR | Up | 0.0275190863 |
| GSE13712_STATIC | Up | 0.0982313880 |
| GSE19018 | Down | -0.4004339889 |
| GSE19899_A1 | Down | -0.1323635899 |
| GSE19899_A2 | Up | 0.9655706474 |
| PubMed_21979375_A1 | Up | 0.8292439088 |
| PubMed_21979375_A2 | Up | 1.9528050439 |
| GSE35957 | Up | 0.0609571027 |
| GSE36640 | Down | -0.1764101418 |
| GSE54402 | Up | 0.5070792603 |
| GSE9593 | Down | -0.1136042569 |
| GSE43922 | Up | 0.0486532994 |
| GSE24585 | Down | -0.0362230908 |
| GSE37065 | Up | 0.0166644988 |
| GSE28863_A1 | Down | -0.1295136204 |
| GSE28863_A2 | Down | -0.0252958350 |
| GSE28863_A3 | Up | 0.1278064895 |
| GSE28863_A4 | Down | -0.0888643142 |
| GSE48662 | Up | 0.0685092473 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-296-3p | MIMAT0004679 | MIRT038362 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-423-3p | MIMAT0001340 | MIRT042581 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-10a-5p | MIMAT0000253 | MIRT047686 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-let-7c-5p | MIMAT0000064 | MIRT051835 | CLASH | Functional MTI (Weak) | 23622248 |
Entries Per Page
Displaying Page of
- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
