HCSGD entry for STAM2


1. General information

Official gene symbolSTAM2
Entrez ID10254
Gene full namesignal transducing adaptor molecule (SH3 domain and ITAM motif) 2
Other gene symbolsHbp STAM2A STAM2B
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0005515Protein bindingIPImolecular_function
GO:0005634NucleusIDAcellular_component
GO:0005730NucleolusIDAcellular_component
GO:0005737CytoplasmIDAcellular_component
GO:0005829CytosolTAScellular_component
GO:0006886Intracellular protein transportIEAbiological_process
GO:0007173Epidermal growth factor receptor signaling pathwayTASbiological_process
GO:0016197Endosomal transportTASbiological_process
GO:0031901Early endosome membraneIEAcellular_component
GO:0042059Negative regulation of epidermal growth factor receptor signaling pathwayTASbiological_process
GO:0043231Intracellular membrane-bounded organelleIDAcellular_component
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.87261328220.09237947650.99999024730.5787955725

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.0018966202
GSE13712_SHEARUp0.0941066755
GSE13712_STATICUp0.0749975511
GSE19018Down-0.1449263119
GSE19899_A1Down-0.0235014003
GSE19899_A2Down-0.1577630795
PubMed_21979375_A1Down-0.4742894814
PubMed_21979375_A2Down-0.2180093915
GSE35957Down-0.0139395905
GSE36640Up0.3885792586
GSE54402Down-0.0703435615
GSE9593Down-0.0498339363
GSE43922Down-0.0072516095
GSE24585Up0.6284615663
GSE37065Up0.0911178795
GSE28863_A1Down-0.2573232074
GSE28863_A2Down-0.0011817464
GSE28863_A3Down-0.8423874641
GSE28863_A4Down-0.3186149029
GSE48662Down-0.4011630278

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-218-5pMIMAT0000275MIRT005005Luciferase reporter assay//qRT-PCRNon-Functional MTI19890957
hsa-miR-34a-5pMIMAT0000255MIRT025220ProteomicsFunctional MTI (Weak)21566225
hsa-miR-744-5pMIMAT0004945MIRT037384CLASHFunctional MTI (Weak)23622248
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  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.