HCSGD entry for GPHN

1. General information

Official gene symbolGPHN
Entrez ID10243
Gene full namegephyrin
Other gene symbolsGEPH GPH GPHRYN HKPX1
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0005524ATP bindingIEAmolecular_function
GO:0005737CytoplasmIEAcellular_component
GO:0005856CytoskeletonIEAcellular_component
GO:0005886Plasma membraneTAScellular_component
GO:0006766Vitamin metabolic processTASbiological_process
GO:0006767Water-soluble vitamin metabolic processTASbiological_process
GO:0006777Mo-molybdopterin cofactor biosynthetic processIEAbiological_process
GO:0007529Establishment of synaptic specificity at neuromuscular junctionIEAbiological_process
GO:0016740Transferase activityTASmolecular_function
GO:0030054Cell junctionIEAcellular_component
GO:0032324Molybdopterin cofactor biosynthetic processTASbiological_process
GO:0044281Small molecule metabolic processTASbiological_process
GO:0045211Postsynaptic membraneIEAcellular_component
GO:0046872Metal ion bindingIEAmolecular_function
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.86822388210.11322947840.99999024730.6449498161

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.0614700835
GSE13712_SHEARDown-0.5139166149
GSE13712_STATICDown-0.1000896014
GSE19018Down-0.0458810521
GSE19899_A1Up0.1104183038
GSE19899_A2Down-0.4184203141
PubMed_21979375_A1Up0.3788271314
PubMed_21979375_A2Up0.1763746696
GSE35957Down-0.4251877846
GSE36640Down-0.5963860090
GSE54402Up0.0572096679
GSE9593Down-0.3041672993
GSE43922Up0.0524672386
GSE24585Up0.0047668230
GSE37065Down-0.0904523519
GSE28863_A1Up0.3248233169
GSE28863_A2Down-0.3884718654
GSE28863_A3Down-0.3958103893
GSE28863_A4Down-0.0175567544
GSE48662Down-0.4970461859

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Name

Drug

Accession number

Formic AcidDB01942 EXPT01461
Propanoic AcidDB03766 EXPT02641

  • MicroRNAs

  • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-let-7b-5pMIMAT0000063MIRT052292CLASHFunctional MTI (Weak)23622248
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  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.