HCSGD entry for DCAF7
1. General information
| Official gene symbol | DCAF7 |
|---|---|
| Entrez ID | 10238 |
| Gene full name | DDB1 and CUL4 associated factor 7 |
| Other gene symbols | AN11 HAN11 SWAN-1 WDR68 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005634 | Nucleus | IDA | cellular_component |
| GO:0005730 | Nucleolus | IDA | cellular_component |
| GO:0005737 | Cytoplasm | IDA TAS | cellular_component |
| GO:0007275 | Multicellular organismal development | IEA | biological_process |
| GO:0016363 | Nuclear matrix | IDA | cellular_component |
| GO:0016567 | Protein ubiquitination | IC IEA | biological_process |
| GO:0043234 | Protein complex | IDA | cellular_component |
| GO:0080008 | Cul4-RING ubiquitin ligase complex | IDA | cellular_component |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.0777428441 | 0.9644382470 | 0.5883465785 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.0781084362 |
| GSE13712_SHEAR | Up | 0.6047534626 |
| GSE13712_STATIC | Up | 0.2651298389 |
| GSE19018 | Up | 0.1621398154 |
| GSE19899_A1 | Up | 0.3317442140 |
| GSE19899_A2 | Up | 0.3234033960 |
| PubMed_21979375_A1 | Down | -0.0924222958 |
| PubMed_21979375_A2 | Up | 0.3324171471 |
| GSE35957 | Up | 0.0250979543 |
| GSE36640 | Up | 0.1362520759 |
| GSE54402 | Down | -0.0564655566 |
| GSE9593 | Down | -0.0403661839 |
| GSE43922 | Up | 0.2893711047 |
| GSE24585 | Up | 0.3764471033 |
| GSE37065 | Down | -0.0092183595 |
| GSE28863_A1 | Up | 0.1611987308 |
| GSE28863_A2 | Up | 0.1821055450 |
| GSE28863_A3 | Down | -0.2646703417 |
| GSE28863_A4 | Down | -0.1280836384 |
| GSE48662 | Up | 0.1515731922 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-155-5p | MIMAT0000646 | MIRT005255 | pSILAC//Proteomics | Functional MTI (Weak) | 18668040 |
| hsa-miR-193b-3p | MIMAT0002819 | MIRT016519 | Microarray | Functional MTI (Weak) | 20304954 |
| hsa-miR-7-5p | MIMAT0000252 | MIRT025855 | Microarray | Functional MTI (Weak) | 19073608 |
| hsa-miR-19b-3p | MIMAT0000074 | MIRT031255 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-miR-16-5p | MIMAT0000069 | MIRT031778 | Proteomics | Functional MTI (Weak) | 18668040 |
| hsa-miR-1229-3p | MIMAT0005584 | MIRT036382 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-760 | MIMAT0004957 | MIRT036725 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-326 | MIMAT0000756 | MIRT043645 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-222-3p | MIMAT0000279 | MIRT046679 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-26a-5p | MIMAT0000082 | MIRT050075 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-18a-5p | MIMAT0000072 | MIRT050673 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-let-7c-5p | MIMAT0000064 | MIRT051762 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-let-7b-5p | MIMAT0000063 | MIRT051938 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: 1 abstracts the gene occurs.
PubMed ID of the article | Sentenece the gene occurs |
|---|---|
| 24478790 | These two loci harbor a number of novel candidate genes with SNPs, and our gene-wise association analysis identified multiple genes, including DCAF7, POLG2, CEP95, and SMURF2 at 17q23 |
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