HCSGD entry for EIF1
1. General information
| Official gene symbol | EIF1 |
|---|---|
| Entrez ID | 10209 |
| Gene full name | eukaryotic translation initiation factor 1 |
| Other gene symbols | A121 EIF-1 EIF1A ISO1 SUI1 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0003743 | Translation initiation factor activity | IEA NAS | molecular_function |
| GO:0005737 | Cytoplasm | TAS | cellular_component |
| GO:0006446 | Regulation of translational initiation | TAS | biological_process |
| GO:0006950 | Response to stress | NAS | biological_process |
| GO:0008135 | Translation factor activity, nucleic acid binding | TAS | molecular_function |
| GO:0009048 | Dosage compensation by inactivation of X chromosome | IEA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.5069014551 | 0.5804870028 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.1100003647 |
| GSE13712_SHEAR | Up | 0.0750096218 |
| GSE13712_STATIC | Up | 0.0257627534 |
| GSE19018 | Down | -0.2246844372 |
| GSE19899_A1 | Down | -0.0738735777 |
| GSE19899_A2 | Down | -0.1310574296 |
| PubMed_21979375_A1 | Up | 0.1858683394 |
| PubMed_21979375_A2 | Down | -0.3053053197 |
| GSE35957 | Up | 0.0250445881 |
| GSE36640 | Up | 0.0067311941 |
| GSE54402 | Up | 0.0909177933 |
| GSE9593 | Up | 0.1909753935 |
| GSE43922 | Up | 0.0167329011 |
| GSE24585 | Up | 0.0252579940 |
| GSE37065 | Down | -0.0969695758 |
| GSE28863_A1 | Up | 0.8773505217 |
| GSE28863_A2 | Up | 0.5631260305 |
| GSE28863_A3 | Down | -0.3428610007 |
| GSE28863_A4 | Up | 0.0802656934 |
| GSE48662 | Down | -0.1354026416 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-30a-5p | MIMAT0000087 | MIRT028444 | Proteomics | Functional MTI (Weak) | 18668040 |
| hsa-miR-16-5p | MIMAT0000069 | MIRT031390 | Proteomics | Functional MTI (Weak) | 18668040 |
| hsa-miR-193b-3p | MIMAT0002819 | MIRT041198 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-186-5p | MIMAT0000456 | MIRT044979 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-10b-5p | MIMAT0000254 | MIRT047434 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-10a-5p | MIMAT0000253 | MIRT047677 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
