HCSGD entry for CALCRL

1. General information

Official gene symbolCALCRL
Entrez ID10203
Gene full namecalcitonin receptor-like
Other gene symbolsCGRPR CRLR
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0001525AngiogenesisIDAbiological_process
GO:0001605Adrenomedullin receptor activityIDAmolecular_function
GO:0001635Calcitonin gene-related polypeptide receptor activityIEAmolecular_function
GO:0004930G-protein coupled receptor activityTASmolecular_function
GO:0004948Calcitonin receptor activityIEAmolecular_function
GO:0005515Protein bindingIPImolecular_function
GO:0005764LysosomeIDAcellular_component
GO:0005768EndosomeIDAcellular_component
GO:0005783Endoplasmic reticulumIDAcellular_component
GO:0005886Plasma membraneIDA TAScellular_component
GO:0005887Integral component of plasma membraneTAScellular_component
GO:0006171CAMP biosynthetic processIDAbiological_process
GO:0006816Calcium ion transportIDAbiological_process
GO:0006937Regulation of muscle contractionIEAbiological_process
GO:0007187G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messengerTASbiological_process
GO:0007189Adenylate cyclase-activating G-protein coupled receptor signaling pathwayIEAbiological_process
GO:0007507Heart developmentIEAbiological_process
GO:0008565Protein transporter activityIDAmolecular_function
GO:0015031Protein transportIDAbiological_process
GO:0016020MembraneIEAcellular_component
GO:0030819Positive regulation of cAMP biosynthetic processIDAbiological_process
GO:0031623Receptor internalizationIDAbiological_process
GO:0048661Positive regulation of smooth muscle cell proliferationIEAbiological_process
GO:0050728Negative regulation of inflammatory responseIEAbiological_process
GO:0071329Cellular response to sucrose stimulusIDAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.06240526580.10144078490.53988373320.6098799452

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.3993937638
GSE13712_SHEARDown-1.2911180188
GSE13712_STATICDown-1.0551071491
GSE19018Up0.1402715647
GSE19899_A1Up0.1780336229
GSE19899_A2Down-0.0008484112
PubMed_21979375_A1Up0.2466521757
PubMed_21979375_A2Up0.1560018773
GSE35957Up0.1228156677
GSE36640Down-0.4314915319
GSE54402Up0.7283145035
GSE9593Down-0.1125866615
GSE43922Up0.5757199406
GSE24585Up2.6927838126
GSE37065Down-0.4333036675
GSE28863_A1Down-0.3107479434
GSE28863_A2Down-0.7095540598
GSE28863_A3Down-0.0410979055
GSE28863_A4Down-0.1595131576
GSE48662Up0.1861430662

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-124-3pMIMAT0000422MIRT022193MicroarrayFunctional MTI (Weak)18668037
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  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.