HCSGD entry for ALG3
1. General information
| Official gene symbol | ALG3 |
|---|---|
| Entrez ID | 10195 |
| Gene full name | ALG3, alpha-1,3- mannosyltransferase |
| Other gene symbols | CDG1D CDGS4 D16Ertd36e NOT56L Not56 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0000033 | Alpha-1,3-mannosyltransferase activity | IDA | molecular_function |
| GO:0005783 | Endoplasmic reticulum | IEA | cellular_component |
| GO:0005789 | Endoplasmic reticulum membrane | IDA TAS | cellular_component |
| GO:0006486 | Protein glycosylation | NAS | biological_process |
| GO:0006488 | Dolichol-linked oligosaccharide biosynthetic process | TAS | biological_process |
| GO:0016021 | Integral component of membrane | IEA | cellular_component |
| GO:0016758 | Transferase activity, transferring hexosyl groups | IEA | molecular_function |
| GO:0018279 | Protein N-linked glycosylation via asparagine | TAS | biological_process |
| GO:0043687 | Post-translational protein modification | TAS | biological_process |
| GO:0044267 | Cellular protein metabolic process | TAS | biological_process |
| GO:0052925 | Dol-P-Man:Man(5)GlcNAc(2)-PP-Dol alpha-1,3-mannosyltransferase activity | IEA | molecular_function |
| GO:0097502 | Mannosylation | IDA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.0151829718 | 0.7792321150 | 0.3064654908 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.9060335183 |
| GSE13712_SHEAR | Down | -0.2377967429 |
| GSE13712_STATIC | Up | 0.0205804212 |
| GSE19018 | Up | 0.1270339854 |
| GSE19899_A1 | Up | 0.3578482792 |
| GSE19899_A2 | Up | 1.2985542675 |
| PubMed_21979375_A1 | Up | 1.9118474895 |
| PubMed_21979375_A2 | Up | 1.6019876324 |
| GSE35957 | Down | -0.1681416681 |
| GSE36640 | Up | 0.4395779880 |
| GSE54402 | Up | 0.4066360221 |
| GSE9593 | Down | -0.0823472583 |
| GSE43922 | Up | 0.6304394087 |
| GSE24585 | Down | -0.4125490191 |
| GSE37065 | Down | -0.0227599393 |
| GSE28863_A1 | Down | -0.1640989304 |
| GSE28863_A2 | Up | 0.1960835152 |
| GSE28863_A3 | Down | -0.4141013021 |
| GSE28863_A4 | Down | -0.1309998427 |
| GSE48662 | Down | -0.2806755682 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-let-7b-5p | MIMAT0000063 | MIRT005225 | pSILAC//Proteomics;Other | Functional MTI (Weak) | 18668040 |
| hsa-miR-16-5p | MIMAT0000069 | MIRT005258 | pSILAC//Proteomics;Other | Functional MTI (Weak) | 18668040 |
| hsa-miR-16-5p | MIMAT0000069 | MIRT005258 | Microarray | Functional MTI (Weak) | 21199864 |
| hsa-miR-1 | MIMAT0000416 | MIRT023511 | Proteomics | Functional MTI (Weak) | 18668040 |
| hsa-miR-7-5p | MIMAT0000252 | MIRT025687 | Microarray | Functional MTI (Weak) | 19073608 |
| hsa-miR-98-5p | MIMAT0000096 | MIRT027484 | Microarray | Functional MTI (Weak) | 19088304 |
| hsa-miR-26b-5p | MIMAT0000083 | MIRT028778 | Microarray | Functional MTI (Weak) | 19088304 |
| hsa-miR-222-3p | MIMAT0000279 | MIRT046832 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-100-5p | MIMAT0000098 | MIRT048444 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
