HCSGD entry for RNF41
1. General information
| Official gene symbol | RNF41 |
|---|---|
| Entrez ID | 10193 |
| Gene full name | ring finger protein 41 |
| Other gene symbols | FLRF NRDP1 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0000209 | Protein polyubiquitination | IDA | biological_process |
| GO:0004842 | Ubiquitin-protein ligase activity | IDA IEA TAS | molecular_function |
| GO:0005128 | Erythropoietin receptor binding | IEA | molecular_function |
| GO:0005135 | Interleukin-3 receptor binding | IEA | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005829 | Cytosol | TAS | cellular_component |
| GO:0008270 | Zinc ion binding | IEA | molecular_function |
| GO:0008285 | Negative regulation of cell proliferation | IDA | biological_process |
| GO:0030336 | Negative regulation of cell migration | IMP | biological_process |
| GO:0031386 | Protein tag | IEA | molecular_function |
| GO:0043408 | Regulation of MAPK cascade | IDA | biological_process |
| GO:0045619 | Regulation of lymphocyte differentiation | IEA | biological_process |
| GO:0045637 | Regulation of myeloid cell differentiation | IEA | biological_process |
| GO:0051896 | Regulation of protein kinase B signaling | IDA | biological_process |
| GO:0097191 | Extrinsic apoptotic signaling pathway | IDA | biological_process |
| GO:2000377 | Regulation of reactive oxygen species metabolic process | IMP | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.4363172866 | 0.0458832187 | 0.9999902473 | 0.4017605456 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.1995029293 |
| GSE13712_SHEAR | Up | 0.0493628179 |
| GSE13712_STATIC | Down | -0.5694912570 |
| GSE19018 | Down | -0.0776136465 |
| GSE19899_A1 | Down | -0.3168730916 |
| GSE19899_A2 | Up | 0.5398473641 |
| PubMed_21979375_A1 | Down | -0.3203245281 |
| PubMed_21979375_A2 | Down | -0.2486146880 |
| GSE35957 | Up | 0.5119925927 |
| GSE36640 | Up | 1.3006102408 |
| GSE54402 | Up | 0.0483542815 |
| GSE9593 | Up | 0.4857541932 |
| GSE43922 | Up | 0.0052603618 |
| GSE24585 | Up | 0.0287449894 |
| GSE37065 | Down | -0.3992718209 |
| GSE28863_A1 | Down | -0.4730824148 |
| GSE28863_A2 | Down | -0.5415681703 |
| GSE28863_A3 | Down | -0.8430502128 |
| GSE28863_A4 | Up | 0.1866605582 |
| GSE48662 | Up | 0.2049536432 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-130b-3p | MIMAT0000691 | MIRT020324 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-miR-183-5p | MIMAT0000261 | MIRT025017 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-miR-7-5p | MIMAT0000252 | MIRT025964 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-miR-19b-3p | MIMAT0000074 | MIRT031241 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-miR-877-5p | MIMAT0004949 | MIRT037304 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-708-5p | MIMAT0004926 | MIRT037744 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-320a | MIMAT0000510 | MIRT044633 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
