HCSGD entry for SLC25A15
1. General information
| Official gene symbol | SLC25A15 |
|---|---|
| Entrez ID | 10166 |
| Gene full name | solute carrier family 25 (mitochondrial carrier; ornithine transporter) member 15 |
| Other gene symbols | D13S327 HHH ORC1 ORNT1 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0000050 | Urea cycle | TAS | biological_process |
| GO:0000064 | L-ornithine transmembrane transporter activity | TAS | molecular_function |
| GO:0000066 | Mitochondrial ornithine transport | TAS | biological_process |
| GO:0003333 | Amino acid transmembrane transport | TAS | biological_process |
| GO:0005743 | Mitochondrial inner membrane | IEA TAS | cellular_component |
| GO:0006520 | Cellular amino acid metabolic process | TAS | biological_process |
| GO:0006810 | Transport | IEA | biological_process |
| GO:0015807 | L-amino acid transport | TAS | biological_process |
| GO:0016021 | Integral component of membrane | IEA | cellular_component |
| GO:0034220 | Ion transmembrane transport | TAS | biological_process |
| GO:0034641 | Cellular nitrogen compound metabolic process | TAS | biological_process |
| GO:0044281 | Small molecule metabolic process | TAS | biological_process |
| GO:0055085 | Transmembrane transport | TAS | biological_process |
| GO:1902475 | L-alpha-amino acid transmembrane transport | TAS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.0796030356 | 0.0402409141 | 0.5940548625 | 0.3788201359 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.2463209969 |
| GSE13712_SHEAR | Down | -0.0174908973 |
| GSE13712_STATIC | Up | 0.3361277696 |
| GSE19018 | Down | -0.8355777464 |
| GSE19899_A1 | Up | 0.0661917832 |
| GSE19899_A2 | Up | 0.9629642351 |
| PubMed_21979375_A1 | Up | 1.1074548561 |
| PubMed_21979375_A2 | Up | 1.3707230536 |
| GSE35957 | Down | -0.5724468007 |
| GSE36640 | Up | 0.3607834058 |
| GSE54402 | Up | 0.9470875750 |
| GSE9593 | Down | -0.6984948747 |
| GSE43922 | Up | 1.0782688135 |
| GSE24585 | Down | -0.2177813348 |
| GSE37065 | Down | -0.5652429493 |
| GSE28863_A1 | Down | -0.3353393280 |
| GSE28863_A2 | Down | -0.6638516080 |
| GSE28863_A3 | Down | -0.4660295886 |
| GSE28863_A4 | Down | -0.0000130358 |
| GSE48662 | Down | -0.2779823754 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Name | Drug | Accession number |
|---|---|---|
| L-Ornithine | DB00129 | NUTR00043 |
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-193b-3p | MIMAT0002819 | MIRT016548 | Microarray | Functional MTI (Weak) | 20304954 |
| hsa-miR-375 | MIMAT0000728 | MIRT020002 | Microarray | Functional MTI (Weak) | 20215506 |
| hsa-miR-7-5p | MIMAT0000252 | MIRT025968 | Microarray | Functional MTI (Weak) | 19073608 |
| hsa-miR-7-5p | MIMAT0000252 | MIRT025968 | Microarray | Functional MTI (Weak) | 17612493 |
| hsa-miR-24-3p | MIMAT0000080 | MIRT030568 | Microarray | Functional MTI (Weak) | 19748357 |
| hsa-miR-423-3p | MIMAT0001340 | MIRT042626 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
