HCSGD entry for WASF2
1. General information
| Official gene symbol | WASF2 |
|---|---|
| Entrez ID | 10163 |
| Gene full name | WAS protein family, member 2 |
| Other gene symbols | IMD2 SCAR2 WASF4 WAVE2 dJ393P12.2 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0001525 | Angiogenesis | IEA | biological_process |
| GO:0001667 | Ameboidal cell migration | IEA | biological_process |
| GO:0001726 | Ruffle | IEA | cellular_component |
| GO:0003779 | Actin binding | IEA | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005622 | Intracellular | IDA | cellular_component |
| GO:0005769 | Early endosome | IEA | cellular_component |
| GO:0005829 | Cytosol | TAS | cellular_component |
| GO:0007188 | Adenylate cyclase-modulating G-protein coupled receptor signaling pathway | TAS | biological_process |
| GO:0015629 | Actin cytoskeleton | TAS | cellular_component |
| GO:0016601 | Rac protein signal transduction | IEA | biological_process |
| GO:0030027 | Lamellipodium | IDA | cellular_component |
| GO:0030032 | Lamellipodium assembly | IEA | biological_process |
| GO:0030036 | Actin cytoskeleton organization | IEA | biological_process |
| GO:0030048 | Actin filament-based movement | IEA | biological_process |
| GO:0035855 | Megakaryocyte development | IEA | biological_process |
| GO:0038096 | Fc-gamma receptor signaling pathway involved in phagocytosis | TAS | biological_process |
| GO:0045087 | Innate immune response | TAS | biological_process |
| GO:0072673 | Lamellipodium morphogenesis | IEA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.6943431595 | 0.0772523004 | 0.9999902473 | 0.5256871251 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.1670600731 |
| GSE13712_SHEAR | Down | -0.3932824087 |
| GSE13712_STATIC | Down | -0.2815115503 |
| GSE19018 | Up | 0.2988803862 |
| GSE19899_A1 | Down | -0.2378894513 |
| GSE19899_A2 | Down | -0.2495132303 |
| PubMed_21979375_A1 | Down | -0.1850571023 |
| PubMed_21979375_A2 | Up | 0.2378994415 |
| GSE35957 | Down | -0.4842881437 |
| GSE36640 | Down | -0.4834265103 |
| GSE54402 | Down | -0.1844914429 |
| GSE9593 | Down | -0.1762432042 |
| GSE43922 | Up | 0.0114127925 |
| GSE24585 | Up | 0.1546192814 |
| GSE37065 | Down | -0.0992544375 |
| GSE28863_A1 | Up | 0.0165103748 |
| GSE28863_A2 | Down | -0.1586960733 |
| GSE28863_A3 | Up | 0.0851184533 |
| GSE28863_A4 | Down | -0.3082218159 |
| GSE48662 | Up | 0.7866416829 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-146a-5p | MIMAT0000449 | MIRT007243 | Luciferase reporter assay | Functional MTI | 23435376 |
| hsa-miR-124-3p | MIMAT0000422 | MIRT022583 | Microarray | Functional MTI (Weak) | 18668037 |
| hsa-miR-1 | MIMAT0000416 | MIRT023756 | Proteomics;Microarray | Functional MTI (Weak) | 18668037 |
| hsa-miR-34a-5p | MIMAT0000255 | MIRT025275 | Proteomics | Functional MTI (Weak) | 21566225 |
| hsa-miR-7-5p | MIMAT0000252 | MIRT025754 | Microarray | Functional MTI (Weak) | 19073608 |
| hsa-miR-7-5p | MIMAT0000252 | MIRT025754 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-26b-5p | MIMAT0000083 | MIRT029364 | Microarray | Functional MTI (Weak) | 19088304 |
| hsa-miR-1224-5p | MIMAT0005458 | MIRT036553 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-940 | MIMAT0004983 | MIRT036610 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-877-3p | MIMAT0004950 | MIRT037001 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-425-5p | MIMAT0003393 | MIRT039325 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
