HCSGD entry for ABI2


1. General information

Official gene symbolABI2
Entrez ID10152
Gene full nameabl-interactor 2
Other gene symbolsABI-2 ABI2B AIP-1 AblBP3 SSH3BP2 argBPIA argBPIB
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0003677DNA bindingTASmolecular_function
GO:0005515Protein bindingIPImolecular_function
GO:0005737CytoplasmIEA TAScellular_component
GO:0005829CytosolIDAcellular_component
GO:0005856CytoskeletonIEAcellular_component
GO:0005913Cell-cell adherens junctionIEAcellular_component
GO:0006928Cellular component movementIDAbiological_process
GO:0007010Cytoskeleton organizationTASbiological_process
GO:0007611Learning or memoryIEAbiological_process
GO:0008093Cytoskeletal adaptor activityTASmolecular_function
GO:0008154Actin polymerization or depolymerizationIEA NASbiological_process
GO:0016358Dendrite developmentIEAbiological_process
GO:0016477Cell migrationTASbiological_process
GO:0017124SH3 domain bindingIPI TASmolecular_function
GO:0018108Peptidyl-tyrosine phosphorylationIDAbiological_process
GO:0019900Kinase bindingNASmolecular_function
GO:0030027LamellipodiumIDAcellular_component
GO:0030175FilopodiumIDAcellular_component
GO:0030296Protein tyrosine kinase activator activityIEAmolecular_function
GO:0030425DendriteIEAcellular_component
GO:0031625Ubiquitin protein ligase bindingIPImolecular_function
GO:0043010Camera-type eye developmentIEAbiological_process
GO:0070064Proline-rich region bindingIPImolecular_function
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.86805508150.17405566660.99999024730.8075928811

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.0269883363
GSE13712_SHEARDown-0.1556315071
GSE13712_STATICDown-0.0839589407
GSE19018Down-0.1108662575
GSE19899_A1Up0.0142679385
GSE19899_A2Down-0.1552105188
PubMed_21979375_A1Down-0.2438249874
PubMed_21979375_A2Down-0.0470563785
GSE35957Down-0.4948901070
GSE36640Down-0.2887580531
GSE54402Up0.2385248078
GSE9593Down-0.2121397429
GSE43922Up0.0015016244
GSE24585Up0.3512794866
GSE37065Down-0.1296413552
GSE28863_A1Up0.3418675859
GSE28863_A2Down-0.0697180511
GSE28863_A3Down-0.5124577747
GSE28863_A4Down-0.2881710588
GSE48662Up0.3987139135

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-193b-3pMIMAT0002819MIRT016520MicroarrayFunctional MTI (Weak)20304954
hsa-miR-331-3pMIMAT0000760MIRT019245SequencingFunctional MTI (Weak)20371350
hsa-miR-375MIMAT0000728MIRT019960MicroarrayFunctional MTI (Weak)20215506
hsa-miR-1224-5pMIMAT0005458MIRT036555CLASHFunctional MTI (Weak)23622248
hsa-miR-30c-5pMIMAT0000244MIRT047875CLASHFunctional MTI (Weak)23622248
hsa-miR-17-5pMIMAT0000070MIRT050912CLASHFunctional MTI (Weak)23622248
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  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.