HCSGD entry for MBNL2
1. General information
| Official gene symbol | MBNL2 |
|---|---|
| Entrez ID | 10150 |
| Gene full name | muscleblind-like splicing regulator 2 |
| Other gene symbols | MBLL MBLL39 PRO2032 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0000381 | Regulation of alternative mRNA splicing, via spliceosome | IEA | biological_process |
| GO:0003723 | RNA binding | IEA | molecular_function |
| GO:0005634 | Nucleus | IEA | cellular_component |
| GO:0005737 | Cytoplasm | IEA | cellular_component |
| GO:0006397 | MRNA processing | IEA | biological_process |
| GO:0008380 | RNA splicing | IEA | biological_process |
| GO:0043484 | Regulation of RNA splicing | IDA | biological_process |
| GO:0046872 | Metal ion binding | IEA | molecular_function |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.8855004939 | 0.0055886364 | 0.9999902473 | 0.1514102881 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.0846779364 |
| GSE13712_SHEAR | Up | 0.5064912280 |
| GSE13712_STATIC | Up | 0.1760168293 |
| GSE19018 | Up | 0.0046062810 |
| GSE19899_A1 | Down | -0.3363589149 |
| GSE19899_A2 | Down | -1.2301178969 |
| PubMed_21979375_A1 | Down | -0.9880466597 |
| PubMed_21979375_A2 | Down | -0.8145584437 |
| GSE35957 | Up | 0.3712224280 |
| GSE36640 | Up | 0.8244376640 |
| GSE54402 | Down | -0.6096138827 |
| GSE9593 | Up | 0.0623820779 |
| GSE43922 | Down | -0.2895950014 |
| GSE24585 | Down | -0.0941593232 |
| GSE37065 | Down | -0.2793965648 |
| GSE28863_A1 | Down | -0.8095895749 |
| GSE28863_A2 | Down | -1.1754719473 |
| GSE28863_A3 | Down | -0.7644076439 |
| GSE28863_A4 | Down | -0.1358262190 |
| GSE48662 | Up | 0.1995493577 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-372-3p | MIMAT0000724 | MIRT000059 | Luciferase reporter assay//Microarray | Functional MTI | 19229866 |
| hsa-miR-302d-3p | MIMAT0000718 | MIRT000093 | Luciferase reporter assay//Microarray | Functional MTI | 19229866 |
| hsa-miR-218-5p | MIMAT0000275 | MIRT001057 | qRT-PCR//Western blot | Non-Functional MTI | 17998940 |
| hsa-miR-335-5p | MIMAT0000765 | MIRT017429 | Microarray | Functional MTI (Weak) | 18185580 |
| hsa-miR-101-3p | MIMAT0000099 | MIRT027297 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-miR-98-5p | MIMAT0000096 | MIRT027556 | Microarray | Functional MTI (Weak) | 19088304 |
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- mirRecord
MicroRNA name | mirBase ID | Target site number | MiRNA mature ID | Test method inter | MiRNA regulation site | Reporter target site | Pubmed ID |
|---|---|---|---|---|---|---|---|
| hsa-miR-302d-3p | MIMAT0000718 | 1 | hsa-miR-302d | 19229866 |
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6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
