HCSGD entry for AKAP9
1. General information
| Official gene symbol | AKAP9 |
|---|---|
| Entrez ID | 10142 |
| Gene full name | A kinase (PRKA) anchor protein (yotiao) 9 |
| Other gene symbols | AKAP-9 AKAP350 AKAP450 CG-NAP HYPERION LQT11 MU-RMS-40.16A PPP1R45 PRKA9 YOTIAO |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0000086 | G2/M transition of mitotic cell cycle | TAS | biological_process |
| GO:0000242 | Pericentriolar material | IEA | cellular_component |
| GO:0000278 | Mitotic cell cycle | TAS | biological_process |
| GO:0005102 | Receptor binding | TAS | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005794 | Golgi apparatus | IDA | cellular_component |
| GO:0005813 | Centrosome | IDA | cellular_component |
| GO:0005829 | Cytosol | TAS | cellular_component |
| GO:0005856 | Cytoskeleton | TAS | cellular_component |
| GO:0006810 | Transport | TAS | biological_process |
| GO:0007165 | Signal transduction | TAS | biological_process |
| GO:0007268 | Synaptic transmission | TAS | biological_process |
| GO:0008076 | Voltage-gated potassium channel complex | IDA | cellular_component |
| GO:0016301 | Kinase activity | IEA | molecular_function |
| GO:0032947 | Protein complex scaffold | IDA | molecular_function |
| GO:0043231 | Intracellular membrane-bounded organelle | IDA | cellular_component |
| GO:0044325 | Ion channel binding | IPI | molecular_function |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.0214234945 | 0.9660762585 | 0.3526502814 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.0320340354 |
| GSE13712_SHEAR | Up | 0.2076471599 |
| GSE13712_STATIC | Up | 0.3991649004 |
| GSE19018 | Up | 0.5484815964 |
| GSE19899_A1 | Up | 0.1363749524 |
| GSE19899_A2 | Up | 0.2890529573 |
| PubMed_21979375_A1 | Down | -0.2003351679 |
| PubMed_21979375_A2 | Up | 0.5109084589 |
| GSE35957 | Up | 0.2452100840 |
| GSE36640 | Up | 0.1609116964 |
| GSE54402 | Down | -0.2515667805 |
| GSE9593 | Down | -0.1525184380 |
| GSE43922 | Up | 0.0398491259 |
| GSE24585 | Up | 0.6765144571 |
| GSE37065 | Up | 0.1803101512 |
| GSE28863_A1 | Up | 0.7155263319 |
| GSE28863_A2 | Up | 1.0599640465 |
| GSE28863_A3 | Down | -0.0789961010 |
| GSE28863_A4 | Down | -0.1664128864 |
| GSE48662 | Up | 0.1450418681 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-192-5p | MIMAT0000222 | MIRT004170 | Microarray | Functional MTI (Weak) | 16822819 |
| hsa-miR-21-5p | MIMAT0000076 | MIRT030952 | Microarray | Functional MTI (Weak) | 19242418 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: 1 abstracts the gene occurs.
PubMed ID of the article | Sentenece the gene occurs |
|---|---|
| 22833545 | Comparative proteomics analysis revealed 24 differentially secreted protein spots including Raf kinase inhibitor protein (RKIP), alpha-Enolase, AKAP9, and MARK4, and the findings were confirmed by Western blot analysis of IR-induced senescent cancer cells |
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