HCSGD entry for PREB
1. General information
| Official gene symbol | PREB |
|---|---|
| Entrez ID | 10113 |
| Gene full name | prolactin regulatory element binding |
| Other gene symbols | SEC12 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0000139 | Golgi membrane | TAS | cellular_component |
| GO:0003677 | DNA binding | IEA | molecular_function |
| GO:0005634 | Nucleus | IEA | cellular_component |
| GO:0005783 | Endoplasmic reticulum | IDA | cellular_component |
| GO:0005789 | Endoplasmic reticulum membrane | TAS | cellular_component |
| GO:0006351 | Transcription, DNA-templated | IEA | biological_process |
| GO:0006355 | Regulation of transcription, DNA-templated | IEA | biological_process |
| GO:0006888 | ER to Golgi vesicle-mediated transport | TAS | biological_process |
| GO:0006987 | Activation of signaling protein activity involved in unfolded protein response | TAS | biological_process |
| GO:0015031 | Protein transport | IEA | biological_process |
| GO:0016021 | Integral component of membrane | IEA | cellular_component |
| GO:0018279 | Protein N-linked glycosylation via asparagine | TAS | biological_process |
| GO:0030968 | Endoplasmic reticulum unfolded protein response | TAS | biological_process |
| GO:0043687 | Post-translational protein modification | TAS | biological_process |
| GO:0044267 | Cellular protein metabolic process | TAS | biological_process |
| GO:0048208 | COPII vesicle coating | TAS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.1106998138 | 0.4655027697 | 0.6876469729 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.2350517651 |
| GSE13712_SHEAR | Up | 0.0778067777 |
| GSE13712_STATIC | Down | -0.0465561299 |
| GSE19018 | Down | -0.2192990665 |
| GSE19899_A1 | Up | 0.0857699393 |
| GSE19899_A2 | Up | 0.2712759818 |
| PubMed_21979375_A1 | Up | 1.1668809800 |
| PubMed_21979375_A2 | Up | 0.2133137423 |
| GSE35957 | Down | -0.0748620103 |
| GSE36640 | Up | 0.0560583599 |
| GSE54402 | Up | 0.3698844198 |
| GSE9593 | Down | -0.1428229145 |
| GSE43922 | Up | 0.2065742654 |
| GSE24585 | Down | -0.7670738140 |
| GSE37065 | Down | -0.2144115511 |
| GSE28863_A1 | Up | 0.2702124924 |
| GSE28863_A2 | Up | 0.6305921403 |
| GSE28863_A3 | Down | -0.4630976141 |
| GSE28863_A4 | Down | -0.1449988555 |
| GSE48662 | Up | 0.2531135632 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-124-3p | MIMAT0000422 | MIRT022830 | Microarray | Functional MTI (Weak) | 18668037 |
| hsa-miR-183-5p | MIMAT0000261 | MIRT047099 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-15a-5p | MIMAT0000068 | MIRT051323 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-let-7a-5p | MIMAT0000062 | MIRT052602 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
