HCSGD entry for ARPC4


1. General information

Official gene symbolARPC4
Entrez ID10093
Gene full nameactin related protein 2/3 complex, subunit 4, 20kDa
Other gene symbolsARC20 P20-ARC
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0005515Protein bindingIPImolecular_function
GO:0005829CytosolTAScellular_component
GO:0005885Arp2/3 protein complexIDA IEAcellular_component
GO:0030041Actin filament polymerizationIEAbiological_process
GO:0030674Protein binding, bridgingIPImolecular_function
GO:0034314Arp2/3 complex-mediated actin nucleationIEAbiological_process
GO:0038096Fc-gamma receptor signaling pathway involved in phagocytosisTASbiological_process
GO:0042995Cell projectionIEAcellular_component
GO:0045010Actin nucleationNASbiological_process
GO:0045087Innate immune responseTASbiological_process
GO:0051015Actin filament bindingNASmolecular_function
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.57903746820.49289907300.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.1383651932
GSE13712_SHEARDown-0.0440426467
GSE13712_STATICDown-0.2252474473
GSE19018Down-0.1807573179
GSE19899_A1Down-0.4333389465
GSE19899_A2Down-0.0708436357
PubMed_21979375_A1Up0.2876065270
PubMed_21979375_A2Down-0.3772658710
GSE35957Up0.0458722180
GSE36640Down-0.2386253809
GSE54402Up0.3739402447
GSE9593Up0.1369421621
GSE43922--
GSE24585--
GSE37065--
GSE28863_A1--
GSE28863_A2--
GSE28863_A3--
GSE28863_A4--
GSE48662Up0.2359110616

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Name

Drug

Accession number

N-[2-(2-methyl-1H-indol-3-yl)ethyl]thiophene-2-carboxamideDB08235 -
(2S)-2-(3-bromophenyl)-3-(5-chloro-2-hydroxyphenyl)-1,3-thiazolidin-4-oneDB08236 -

  • MicroRNAs

  • mirTarBase
No target information from mirTarBase
  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.