HCSGD entry for ARPC5
1. General information
| Official gene symbol | ARPC5 |
|---|---|
| Entrez ID | 10092 |
| Gene full name | actin related protein 2/3 complex, subunit 5, 16kDa |
| Other gene symbols | ARC16 dJ127C7.3 p16-Arc |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0003779 | Actin binding | IEA | molecular_function |
| GO:0005200 | Structural constituent of cytoskeleton | TAS | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005737 | Cytoplasm | TAS | cellular_component |
| GO:0005829 | Cytosol | TAS | cellular_component |
| GO:0005856 | Cytoskeleton | IEA | cellular_component |
| GO:0005885 | Arp2/3 protein complex | TAS | cellular_component |
| GO:0006928 | Cellular component movement | TAS | biological_process |
| GO:0015629 | Actin cytoskeleton | TAS | cellular_component |
| GO:0030036 | Actin cytoskeleton organization | TAS | biological_process |
| GO:0030833 | Regulation of actin filament polymerization | IEA | biological_process |
| GO:0038096 | Fc-gamma receptor signaling pathway involved in phagocytosis | TAS | biological_process |
| GO:0042995 | Cell projection | IEA | cellular_component |
| GO:0045087 | Innate immune response | TAS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.9833293986 | 0.1087322100 | 0.9999902473 | 0.6305222516 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.1358951037 |
| GSE13712_SHEAR | Down | -0.1015236766 |
| GSE13712_STATIC | Down | -0.0469867496 |
| GSE19018 | Down | -0.1633493711 |
| GSE19899_A1 | Down | -0.3246770127 |
| GSE19899_A2 | Down | -0.1436582024 |
| PubMed_21979375_A1 | Down | -0.2190558494 |
| PubMed_21979375_A2 | Down | -0.3520177746 |
| GSE35957 | Up | 0.3005193207 |
| GSE36640 | Down | -0.0753513738 |
| GSE54402 | Up | 0.0755820432 |
| GSE9593 | Up | 0.1035089338 |
| GSE43922 | Up | 0.0012373490 |
| GSE24585 | Down | -0.0671518031 |
| GSE37065 | Down | -0.0897623585 |
| GSE28863_A1 | Down | -0.3106491668 |
| GSE28863_A2 | Down | -0.1145134673 |
| GSE28863_A3 | Down | -0.1077391610 |
| GSE28863_A4 | Down | -0.0692615530 |
| GSE48662 | Down | -0.2706637711 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Name | Drug | Accession number |
|---|---|---|
| N-[2-(2-methyl-1H-indol-3-yl)ethyl]thiophene-2-carboxamide | DB08235 | - |
| (2S)-2-(3-bromophenyl)-3-(5-chloro-2-hydroxyphenyl)-1,3-thiazolidin-4-one | DB08236 | - |
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-22-3p | MIMAT0000077 | MIRT006195 | Immunohistochemistry//Luciferase reporter assay//qRT-PCR//Western blot//EMSA//Microarray | Functional MTI | 22447776 |
| hsa-miR-31-5p | MIMAT0000089 | MIRT004981 | Luciferase reporter assay//qRT-PCR | Non-Functional MTI | 19524507 |
| hsa-miR-125a-5p | MIMAT0000443 | MIRT021283 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-miR-133a-3p | MIMAT0000427 | MIRT021705 | Microarray | Functional MTI (Weak) | 21396852 |
| hsa-miR-1 | MIMAT0000416 | MIRT024056 | Proteomics | Functional MTI (Weak) | 18668040 |
| hsa-miR-10a-5p | MIMAT0000253 | MIRT025613 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-miR-30a-5p | MIMAT0000087 | MIRT028673 | Proteomics | Functional MTI (Weak) | 18668040 |
| hsa-miR-26b-5p | MIMAT0000083 | MIRT030269 | Microarray | Functional MTI (Weak) | 19088304 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
