HCSGD entry for PQBP1
1. General information
| Official gene symbol | PQBP1 |
|---|---|
| Entrez ID | 10084 |
| Gene full name | polyglutamine binding protein 1 |
| Other gene symbols | MRX55 MRXS3 MRXS8 NPW38 RENS1 SHS |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0003677 | DNA binding | TAS | molecular_function |
| GO:0003713 | Transcription coactivator activity | TAS | molecular_function |
| GO:0005634 | Nucleus | IDA | cellular_component |
| GO:0005730 | Nucleolus | IDA | cellular_component |
| GO:0005737 | Cytoplasm | IDA | cellular_component |
| GO:0006351 | Transcription, DNA-templated | IEA | biological_process |
| GO:0006355 | Regulation of transcription, DNA-templated | IEA | biological_process |
| GO:0010494 | Cytoplasmic stress granule | IEA | cellular_component |
| GO:0034063 | Stress granule assembly | IDA | biological_process |
| GO:0071598 | Neuronal ribonucleoprotein granule | IEA | cellular_component |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.1340542875 | 0.4259934501 | 0.7414252784 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.4901323986 |
| GSE13712_SHEAR | Down | -0.1261442305 |
| GSE13712_STATIC | Down | -0.2283144028 |
| GSE19018 | Down | -0.3790883732 |
| GSE19899_A1 | Up | 0.3629121177 |
| GSE19899_A2 | Up | 0.3895044684 |
| PubMed_21979375_A1 | Up | 1.2329517743 |
| PubMed_21979375_A2 | Down | -0.0844523103 |
| GSE35957 | Down | -0.4718695730 |
| GSE36640 | Up | 0.0586210549 |
| GSE54402 | Up | 0.5230095418 |
| GSE9593 | Down | -0.1248070612 |
| GSE43922 | Up | 0.5631149452 |
| GSE24585 | Up | 0.1426287822 |
| GSE37065 | Down | -0.0797585805 |
| GSE28863_A1 | Down | -0.3515675489 |
| GSE28863_A2 | Down | -0.3772486993 |
| GSE28863_A3 | Up | 0.2063507257 |
| GSE28863_A4 | Up | 0.0363334378 |
| GSE48662 | Down | -0.3309904434 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-1 | MIMAT0000416 | MIRT023988 | Proteomics;Microarray | Functional MTI (Weak) | 18668037 |
| hsa-miR-26b-5p | MIMAT0000083 | MIRT030062 | Microarray | Functional MTI (Weak) | 19088304 |
| hsa-miR-615-3p | MIMAT0003283 | MIRT039988 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-149-5p | MIMAT0000450 | MIRT045513 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
