HCSGD entry for DPP3
1. General information
| Official gene symbol | DPP3 |
|---|---|
| Entrez ID | 10072 |
| Gene full name | dipeptidyl-peptidase 3 |
| Other gene symbols | DPPIII |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0004177 | Aminopeptidase activity | IEA | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005634 | Nucleus | IDA | cellular_component |
| GO:0005730 | Nucleolus | IDA | cellular_component |
| GO:0005737 | Cytoplasm | IDA IEA | cellular_component |
| GO:0005886 | Plasma membrane | IDA | cellular_component |
| GO:0006508 | Proteolysis | IDA IEA | biological_process |
| GO:0008237 | Metallopeptidase activity | IEA | molecular_function |
| GO:0008239 | Dipeptidyl-peptidase activity | IDA IEA | molecular_function |
| GO:0008270 | Zinc ion binding | IDA IEA | molecular_function |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.3074255347 | 0.2306747996 | 0.9999902473 | 0.9247795309 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.2493027155 |
| GSE13712_SHEAR | Up | 0.2998145844 |
| GSE13712_STATIC | Up | 0.2433096940 |
| GSE19018 | Down | -0.1177509781 |
| GSE19899_A1 | Down | -0.4437067977 |
| GSE19899_A2 | Up | 0.0418758654 |
| PubMed_21979375_A1 | Up | 0.4304966559 |
| PubMed_21979375_A2 | Up | 0.3515147353 |
| GSE35957 | Down | -0.3557074096 |
| GSE36640 | Up | 0.4388172336 |
| GSE54402 | Up | 0.2135716271 |
| GSE9593 | Down | -0.1825375377 |
| GSE43922 | Down | -0.0258303935 |
| GSE24585 | Down | -0.4753734834 |
| GSE37065 | Down | -0.1851545638 |
| GSE28863_A1 | Down | -0.3580025635 |
| GSE28863_A2 | Up | 0.3086282009 |
| GSE28863_A3 | Down | -0.7207732812 |
| GSE28863_A4 | Up | 0.1152527176 |
| GSE48662 | Up | 0.4328134598 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-1296-5p | MIMAT0005794 | MIRT036150 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-615-3p | MIMAT0003283 | MIRT040357 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-320a | MIMAT0000510 | MIRT044782 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: 1 abstracts the gene occurs.
PubMed ID of the article | Sentenece the gene occurs |
|---|---|
| 7020767 | 110, 421-430) decline exponentially throughout the erythrocyte life-span, with the exception of dipeptidyl aminopeptidase III |
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