HCSGD entry for ABCB6

1. General information

Official gene symbolABCB6
Entrez ID10058
Gene full nameATP-binding cassette, sub-family B (MDR/TAP), member 6
Other gene symbolsABC ABC14 LAN MCOPCB7 MTABC3 PRP umat
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0005524ATP bindingIDA IEAmolecular_function
GO:0005739MitochondrionIDA IEAcellular_component
GO:0005740Mitochondrial envelopeIDAcellular_component
GO:0005741Mitochondrial outer membraneIDA TAScellular_component
GO:0005774Vacuolar membraneIBAcellular_component
GO:0005783Endoplasmic reticulumIDAcellular_component
GO:0005794Golgi apparatusIDAcellular_component
GO:0005886Plasma membraneIDAcellular_component
GO:0006200ATP catabolic processIMPbiological_process
GO:0006779Porphyrin-containing compound biosynthetic processIDAbiological_process
GO:0006810TransportIDAbiological_process
GO:0006879Cellular iron ion homeostasisNASbiological_process
GO:0007420Brain developmentIMPbiological_process
GO:0015232Heme transporter activityTASmolecular_function
GO:0015439Heme-transporting ATPase activityIMPmolecular_function
GO:0015562Efflux transmembrane transporter activityIDAmolecular_function
GO:0015886Heme transportIDA IMPbiological_process
GO:0016021Integral component of membraneIEAcellular_component
GO:0020037Heme bindingIDAmolecular_function
GO:0031307Integral component of mitochondrial outer membraneIDAcellular_component
GO:0042626ATPase activity, coupled to transmembrane movement of substancesIEAmolecular_function
GO:0043190ATP-binding cassette (ABC) transporter complexNAScellular_component
GO:0043588Skin developmentIMPbiological_process
GO:0055085Transmembrane transportTASbiological_process
GO:0070574Cadmium ion transmembrane transportIBAbiological_process
GO:0071585Detoxification of cadmium ionIBAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.97103442500.04666319290.99999024730.4052966018

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.1087155409
GSE13712_SHEARDown-0.4066715474
GSE13712_STATICUp0.4722896954
GSE19018Down-0.0180168164
GSE19899_A1Down-0.0436924792
GSE19899_A2Down-0.3514783198
PubMed_21979375_A1Down-0.8271132654
PubMed_21979375_A2Down-0.2430694105
GSE35957Down-0.4856607654
GSE36640Down-0.0146849307
GSE54402Down-0.1967107957
GSE9593Down-0.2710545244
GSE43922--
GSE24585--
GSE37065--
GSE28863_A1Down-0.0639677936
GSE28863_A2Up0.3354684015
GSE28863_A3Down-0.3948073479
GSE28863_A4Down-0.4870420717
GSE48662Up0.1149361296

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-1MIMAT0000416MIRT023567ProteomicsFunctional MTI (Weak)18668040
hsa-miR-26b-5pMIMAT0000083MIRT029048MicroarrayFunctional MTI (Weak)19088304
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  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: 1 abstracts the gene occurs.


PubMed ID of the article

Sentenece the gene occurs

20031273Telomere length and cognitive function in community-dwelling elders: findings from the Health ABC Study
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