HCSGD entry for MICA
1. General information
| Official gene symbol | MICA |
|---|---|
| Entrez ID | 100507436 |
| Gene full name | MHC class I polypeptide-related sequence A |
| Other gene symbols | MIC-A PERB11.1 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0001913 | T cell mediated cytotoxicity | IBA IDA | biological_process |
| GO:0002418 | Immune response to tumor cell | IDA | biological_process |
| GO:0003823 | Antigen binding | IBA | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005615 | Extracellular space | IDA | cellular_component |
| GO:0005737 | Cytoplasm | IEA | cellular_component |
| GO:0005886 | Plasma membrane | IBA TAS | cellular_component |
| GO:0005887 | Integral component of plasma membrane | IDA | cellular_component |
| GO:0006955 | Immune response | IEA | biological_process |
| GO:0006974 | Cellular response to DNA damage stimulus | IDA | biological_process |
| GO:0009408 | Response to heat | IDA | biological_process |
| GO:0009986 | Cell surface | IDA | cellular_component |
| GO:0016020 | Membrane | IEA | cellular_component |
| GO:0016032 | Viral process | IEA | biological_process |
| GO:0019835 | Cytolysis | IEA | biological_process |
| GO:0019882 | Antigen processing and presentation | IBA IEA | biological_process |
| GO:0030881 | Beta-2-microglobulin binding | IBA IDA | molecular_function |
| GO:0042267 | Natural killer cell mediated cytotoxicity | IBA IDA | biological_process |
| GO:0042742 | Defense response to bacterium | IDA | biological_process |
| GO:0046629 | Gamma-delta T cell activation | IDA | biological_process |
| GO:0046703 | Natural killer cell lectin-like receptor binding | IBA IDA IPI | molecular_function |
| GO:0050776 | Regulation of immune response | TAS | biological_process |
| GO:0051607 | Defense response to virus | IDA | biological_process |
Entries Per Page
Displaying Page of
4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.0002355268 | 0.9994685954 | 0.0436718310 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 1.1487437440 |
| GSE13712_SHEAR | Up | 0.2970367708 |
| GSE13712_STATIC | Down | -0.1719737721 |
| GSE19018 | Up | 1.1532603838 |
| GSE19899_A1 | Up | 0.9689083766 |
| GSE19899_A2 | Up | 1.6637303063 |
| PubMed_21979375_A1 | Up | 0.9882101767 |
| PubMed_21979375_A2 | Up | 1.1866852339 |
| GSE35957 | Up | 0.3479569736 |
| GSE36640 | Up | 2.1396153081 |
| GSE54402 | Up | 0.2229995686 |
| GSE9593 | Up | 0.7425167347 |
| GSE43922 | Up | 0.6368643358 |
| GSE24585 | Up | 0.3003047711 |
| GSE37065 | Up | 0.4517434554 |
| GSE28863_A1 | - | - |
| GSE28863_A2 | - | - |
| GSE28863_A3 | - | - |
| GSE28863_A4 | - | - |
| GSE48662 | Up | 0.2179680716 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-373-3p | MIMAT0000726 | MIRT002551 | Microarray | Functional MTI (Weak) | 15685193 |
| hsa-miR-520b | MIMAT0002843 | MIRT004677 | flow//Luciferase reporter assay//qRT-PCR | Functional MTI | 19109132 |
Entries Per Page
Displaying Page of
- mirRecord
MicroRNA name | mirBase ID | Target site number | MiRNA mature ID | Test method inter | MiRNA regulation site | Reporter target site | Pubmed ID |
|---|---|---|---|---|---|---|---|
| hsa-miR-373-3p | MIMAT0000726 | NA | hsa-miR-373 | 15685193 | |||
| hsa-miR-520b | MIMAT0002843 | NA | hsa-miR-520b | 19109132 |
Entries Per Page
Displaying Page of
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
