HCSGD entry for HMGXB4
1. General information
| Official gene symbol | HMGXB4 |
|---|---|
| Entrez ID | 10042 |
| Gene full name | HMG box domain containing 4 |
| Other gene symbols | HMG2L1 HMGBCG THC211630 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0003677 | DNA binding | IEA | molecular_function |
| GO:0008333 | Endosome to lysosome transport | NAS | biological_process |
| GO:0016055 | Wnt signaling pathway | IEA | biological_process |
| GO:0016589 | NURF complex | IDA | cellular_component |
| GO:0030178 | Negative regulation of Wnt signaling pathway | ISS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.9775259109 | 0.0377249687 | 0.9999902473 | 0.3662703430 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.1285834136 |
| GSE13712_SHEAR | Down | -0.0257722753 |
| GSE13712_STATIC | Down | -0.0042009771 |
| GSE19018 | Up | 0.2002065093 |
| GSE19899_A1 | Down | -0.3959682738 |
| GSE19899_A2 | Down | -0.4447352500 |
| PubMed_21979375_A1 | Down | -0.3924384070 |
| PubMed_21979375_A2 | Down | -0.4808559455 |
| GSE35957 | Down | -0.4953801404 |
| GSE36640 | Down | -0.8055229067 |
| GSE54402 | Up | 0.2431423501 |
| GSE9593 | Down | -0.1898492531 |
| GSE43922 | Down | -0.2170671024 |
| GSE24585 | Down | -0.0952789902 |
| GSE37065 | Up | 0.0526282773 |
| GSE28863_A1 | Down | -0.1316262325 |
| GSE28863_A2 | Down | -0.0662885952 |
| GSE28863_A3 | Down | -0.4670111956 |
| GSE28863_A4 | Up | 0.2212261869 |
| GSE48662 | Down | -0.4691368301 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-221-3p | MIMAT0000278 | MIRT003368 | Reporter assay;Microarray | Non-Functional MTI | 20018759 |
| hsa-miR-186-5p | MIMAT0000456 | MIRT021175 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-miR-30c-5p | MIMAT0000244 | MIRT047935 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
