HCSGD entry for PARP2
1. General information
| Official gene symbol | PARP2 |
|---|---|
| Entrez ID | 10038 |
| Gene full name | poly (ADP-ribose) polymerase 2 |
| Other gene symbols | ADPRT2 ADPRTL2 ADPRTL3 ARTD2 PARP-2 pADPRT-2 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0003677 | DNA binding | IEA | molecular_function |
| GO:0003950 | NAD+ ADP-ribosyltransferase activity | IEA | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005654 | Nucleoplasm | IDA IEA | cellular_component |
| GO:0005730 | Nucleolus | IDA IEA | cellular_component |
| GO:0006281 | DNA repair | TAS | biological_process |
| GO:0006284 | Base-excision repair | IEA | biological_process |
| GO:0006471 | Protein ADP-ribosylation | IEA | biological_process |
| GO:0097191 | Extrinsic apoptotic signaling pathway | IEA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.4421007333 | 0.0706919038 | 0.9999902473 | 0.5016666487 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.4103571076 |
| GSE13712_SHEAR | Down | -0.0728928112 |
| GSE13712_STATIC | Up | 0.1862788084 |
| GSE19018 | Down | -0.0190396833 |
| GSE19899_A1 | Down | -0.1430320551 |
| GSE19899_A2 | Down | -1.1893849706 |
| PubMed_21979375_A1 | Up | 0.2896485018 |
| PubMed_21979375_A2 | Down | -1.0471805034 |
| GSE35957 | Down | -1.1042183135 |
| GSE36640 | Down | -1.2934337836 |
| GSE54402 | Up | 0.2754209411 |
| GSE9593 | Down | -0.4879745184 |
| GSE43922 | Down | -0.0472761101 |
| GSE24585 | Down | -0.0068726846 |
| GSE37065 | Up | 0.2274062583 |
| GSE28863_A1 | Up | 0.1071921902 |
| GSE28863_A2 | Up | 0.4292334025 |
| GSE28863_A3 | Down | -0.1376313523 |
| GSE28863_A4 | Up | 0.2850484037 |
| GSE48662 | Down | -0.2251105628 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- MicroRNAs
- mirTarBase
No target information from mirTarBase
- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
