HCSGD entry for TIMM23
1. General information
| Official gene symbol | TIMM23 |
|---|---|
| Entrez ID | 100287932 |
| Gene full name | translocase of inner mitochondrial membrane 23 homolog (yeast) |
| Other gene symbols | TIM23 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005739 | Mitochondrion | IDA | cellular_component |
| GO:0005743 | Mitochondrial inner membrane | TAS | cellular_component |
| GO:0005744 | Mitochondrial inner membrane presequence translocase complex | IDA | cellular_component |
| GO:0005758 | Mitochondrial intermembrane space | IDA | cellular_component |
| GO:0006626 | Protein targeting to mitochondrion | TAS | biological_process |
| GO:0015450 | P-P-bond-hydrolysis-driven protein transmembrane transporter activity | IEA | molecular_function |
| GO:0016021 | Integral component of membrane | IEA | cellular_component |
| GO:0031305 | Integral component of mitochondrial inner membrane | IDA | cellular_component |
| GO:0044267 | Cellular protein metabolic process | TAS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.9852721515 | 0.0087296303 | 0.9999902473 | 0.1860506883 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.1735115237 |
| GSE13712_SHEAR | Down | -0.3183730908 |
| GSE13712_STATIC | Up | 0.0887322881 |
| GSE19018 | Down | -0.0169274612 |
| GSE19899_A1 | Up | 0.0091386144 |
| GSE19899_A2 | Down | -0.0039403390 |
| PubMed_21979375_A1 | Down | -1.0184341859 |
| PubMed_21979375_A2 | Down | -0.2127091589 |
| GSE35957 | Up | 0.0152222056 |
| GSE36640 | Down | -0.4294601578 |
| GSE54402 | Up | 0.1175229675 |
| GSE9593 | Up | 0.1491492003 |
| GSE43922 | Down | -0.1888501325 |
| GSE24585 | Down | -0.2828849791 |
| GSE37065 | Down | -0.1243527756 |
| GSE28863_A1 | Down | -0.4016311997 |
| GSE28863_A2 | Down | -0.9157329507 |
| GSE28863_A3 | Down | -0.9338752053 |
| GSE28863_A4 | Down | -0.3732435315 |
| GSE48662 | Down | -0.2451560509 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-196a-5p | MIMAT0000226 | MIRT026070 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-let-7b-5p | MIMAT0000063 | MIRT032261 | Proteomics | Functional MTI (Weak) | 18668040 |
| hsa-miR-484 | MIMAT0002174 | MIRT042029 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-125b-5p | MIMAT0000423 | MIRT046055 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
