HCSGD entry for BCL2L10

1. General information

Official gene symbolBCL2L10
Entrez ID10017
Gene full nameBCL2-like 10 (apoptosis facilitator)
Other gene symbolsBCL-B Boo Diva
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0005515Protein bindingIPImolecular_function
GO:0005739MitochondrionIDAcellular_component
GO:0005741Mitochondrial outer membraneIBAcellular_component
GO:0005829CytosolIDAcellular_component
GO:0006919Activation of cysteine-type endopeptidase activity involved in apoptotic processTASbiological_process
GO:0007283SpermatogenesisTASbiological_process
GO:0007292Female gamete generationTASbiological_process
GO:0008630Intrinsic apoptotic signaling pathway in response to DNA damageIBAbiological_process
GO:0016020MembraneTAScellular_component
GO:0016021Integral component of membraneIEAcellular_component
GO:0031965Nuclear membraneIEAcellular_component
GO:0042803Protein homodimerization activityIBAmolecular_function
GO:0043065Positive regulation of apoptotic processIEAbiological_process
GO:0043066Negative regulation of apoptotic processIDA IEAbiological_process
GO:0046982Protein heterodimerization activityIBAmolecular_function
GO:0097192Extrinsic apoptotic signaling pathway in absence of ligandIBAbiological_process
GO:2001240Negative regulation of extrinsic apoptotic signaling pathway in absence of ligandIEAbiological_process
GO:2001243Negative regulation of intrinsic apoptotic signaling pathwayIBAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.49609119710.89051529200.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.0460758822
GSE13712_SHEARUp0.2948568125
GSE13712_STATICUp0.3221416159
GSE19018Up0.0332627002
GSE19899_A1Down-0.0164036910
GSE19899_A2Up0.1235131969
PubMed_21979375_A1Up0.0508450491
PubMed_21979375_A2Down-0.0290096219
GSE35957Up0.1234040602
GSE36640Up0.0592763835
GSE54402Up0.1044201842
GSE9593Down-0.0829291067
GSE43922Up0.1475165578
GSE24585Down-0.1240425214
GSE37065Down-0.0767201405
GSE28863_A1Down-0.1106344260
GSE28863_A2Down-0.1817052772
GSE28863_A3Up0.2417354240
GSE28863_A4Up0.0878046495
GSE48662Up0.1109031086

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase
No target information from mirTarBase
  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.