HCSGD entry for PDCD6IP
1. General information
| Official gene symbol | PDCD6IP |
|---|---|
| Entrez ID | 10015 |
| Gene full name | programmed cell death 6 interacting protein |
| Other gene symbols | AIP1 ALIX DRIP4 HP95 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005737 | Cytoplasm | IDA | cellular_component |
| GO:0005815 | Microtubule organizing center | IEA | cellular_component |
| GO:0005829 | Cytosol | TAS | cellular_component |
| GO:0006915 | Apoptotic process | IEA | biological_process |
| GO:0007049 | Cell cycle | IEA | biological_process |
| GO:0015031 | Protein transport | IEA | biological_process |
| GO:0016032 | Viral process | TAS | biological_process |
| GO:0017124 | SH3 domain binding | IEA | molecular_function |
| GO:0042470 | Melanosome | IEA | cellular_component |
| GO:0046983 | Protein dimerization activity | IEA | molecular_function |
| GO:0048306 | Calcium-dependent protein binding | IPI | molecular_function |
| GO:0051301 | Cell division | IEA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.4319552259 | 0.1860409825 | 0.9999902473 | 0.8361995731 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.4650658820 |
| GSE13712_SHEAR | Down | -0.1669116139 |
| GSE13712_STATIC | Down | -0.1365037494 |
| GSE19018 | Up | 0.0610116784 |
| GSE19899_A1 | Down | -0.3583306225 |
| GSE19899_A2 | Down | -0.1151652346 |
| PubMed_21979375_A1 | Down | -1.2253560393 |
| PubMed_21979375_A2 | Down | -0.0362442224 |
| GSE35957 | Up | 0.0184280465 |
| GSE36640 | Up | 0.1511328496 |
| GSE54402 | Down | -0.1891121998 |
| GSE9593 | Up | 0.0249442276 |
| GSE43922 | Up | 0.0738973183 |
| GSE24585 | Up | 0.0304548251 |
| GSE37065 | Up | 0.1376227978 |
| GSE28863_A1 | Down | -0.0317320698 |
| GSE28863_A2 | Down | -0.0816926210 |
| GSE28863_A3 | Up | 0.6252246700 |
| GSE28863_A4 | Up | 0.3100191790 |
| GSE48662 | Up | 0.0893531769 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-16-5p | MIMAT0000069 | MIRT000887 | Microarray | Functional MTI (Weak) | 18362358 |
| hsa-miR-15a-5p | MIMAT0000068 | MIRT000888 | Microarray | Functional MTI (Weak) | 18362358 |
| hsa-miR-760 | MIMAT0004957 | MIRT036759 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-23b-3p | MIMAT0000418 | MIRT046335 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-92a-3p | MIMAT0000092 | MIRT049273 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-23a-3p | MIMAT0000078 | MIRT050434 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
MicroRNA name | mirBase ID | Target site number | MiRNA mature ID | Test method inter | MiRNA regulation site | Reporter target site | Pubmed ID |
|---|---|---|---|---|---|---|---|
| hsa-miR-15a-5p | MIMAT0000068 | NA | hsa-miR-15a | 18362358 | |||
| hsa-miR-16-5p | MIMAT0000069 | NA | hsa-miR-16 | 18362358 |
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6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
