HCSGD entry for KIR2DS2
1. General information
| Official gene symbol | KIR2DS2 |
|---|---|
| Entrez ID | 100132285 |
| Gene full name | killer cell immunoglobulin-like receptor, two domains, short cytoplasmic tail, 2 |
| Other gene symbols | 183ActI CD158J CD158b NKAT5 cl-49 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0004888 | Transmembrane signaling receptor activity | NAS | molecular_function |
| GO:0005886 | Plasma membrane | TAS | cellular_component |
| GO:0006955 | Immune response | NAS | biological_process |
| GO:0007165 | Signal transduction | NAS | biological_process |
| GO:0016021 | Integral component of membrane | NAS | cellular_component |
| GO:0045087 | Innate immune response | TAS | biological_process |
| GO:0050776 | Regulation of immune response | TAS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.6188041906 | 0.9058218533 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.1375900599 |
| GSE13712_SHEAR | Down | -0.0357034936 |
| GSE13712_STATIC | Up | 0.0668096884 |
| GSE19018 | Up | 0.1222374261 |
| GSE19899_A1 | Up | 0.1284278221 |
| GSE19899_A2 | Up | 0.1793527973 |
| PubMed_21979375_A1 | Down | -0.1571761379 |
| PubMed_21979375_A2 | Up | 0.2719960565 |
| GSE35957 | Down | -0.0570545395 |
| GSE36640 | Up | 0.2275233646 |
| GSE54402 | Up | 0.0358058579 |
| GSE9593 | Up | 0.0317828810 |
| GSE43922 | - | - |
| GSE24585 | - | - |
| GSE37065 | - | - |
| GSE28863_A1 | - | - |
| GSE28863_A2 | - | - |
| GSE28863_A3 | - | - |
| GSE28863_A4 | - | - |
| GSE48662 | Down | -0.0423049298 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
No target information from mirTarBase
- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: 1 abstracts the gene occurs.
PubMed ID of the article | Sentenece the gene occurs |
|---|---|
| 26046815 | Our studies demonstrate that endogenous IFN produced by already senescent cells contribute to increased expression of the natural killer (NK) receptor ligands, including MIC-A and ULBP2 |
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