HCSGD entry for GNPDA1
1. General information
| Official gene symbol | GNPDA1 |
|---|---|
| Entrez ID | 10007 |
| Gene full name | glucosamine-6-phosphate deaminase 1 |
| Other gene symbols | GNP1 GNPDA GNPI GPI HLN |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0004342 | Glucosamine-6-phosphate deaminase activity | IEA IMP | molecular_function |
| GO:0005737 | Cytoplasm | IEA ISS | cellular_component |
| GO:0005975 | Carbohydrate metabolic process | IEA | biological_process |
| GO:0006043 | Glucosamine catabolic process | IMP | biological_process |
| GO:0006044 | N-acetylglucosamine metabolic process | IEA | biological_process |
| GO:0006091 | Generation of precursor metabolites and energy | IMP | biological_process |
| GO:0007338 | Single fertilization | TAS | biological_process |
| GO:0016787 | Hydrolase activity | IEA | molecular_function |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.0195944113 | 0.8090789294 | 0.3408754131 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 1.3678785639 |
| GSE13712_SHEAR | Down | -0.0380196817 |
| GSE13712_STATIC | Up | 0.3160566432 |
| GSE19018 | Down | -0.0780403262 |
| GSE19899_A1 | Up | 0.3339593227 |
| GSE19899_A2 | Up | 0.4378471717 |
| PubMed_21979375_A1 | Up | 0.4387792711 |
| PubMed_21979375_A2 | Up | 1.4184679138 |
| GSE35957 | Up | 0.2080904731 |
| GSE36640 | Down | -0.8572166492 |
| GSE54402 | Up | 0.4106390861 |
| GSE9593 | Up | 0.5996530235 |
| GSE43922 | Up | 0.1411390525 |
| GSE24585 | Down | -0.2254640672 |
| GSE37065 | Up | 0.0741326516 |
| GSE28863_A1 | Down | -0.3443472991 |
| GSE28863_A2 | Up | 0.4030464278 |
| GSE28863_A3 | Down | -0.2545550353 |
| GSE28863_A4 | Down | -0.1207452057 |
| GSE48662 | Up | 0.1676696274 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Name | Drug | Accession number |
|---|---|---|
| Beta-D-Glucose | DB02379 | EXPT00685 | EXPT00455 | EXPT01603 |
| 2-Deoxy-2-Amino Glucitol-6-Phosphate | DB02445 | EXPT00457 |
| 16g | DB03951 | EXPT00050 |
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-124-3p | MIMAT0000422 | MIRT023004 | Microarray | Functional MTI (Weak) | 18668037 |
| hsa-miR-30b-5p | MIMAT0000420 | MIRT023457 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-miR-34a-5p | MIMAT0000255 | MIRT025551 | Proteomics | Functional MTI (Weak) | 21566225 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
