HCSGD entry for ABI1


1. General information

Official gene symbolABI1
Entrez ID10006
Gene full nameabl-interactor 1
Other gene symbolsABI-1 ABLBP4 E3B1 NAP1BP SSH3BP SSH3BP1
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0001756SomitogenesisIEAbiological_process
GO:0005515Protein bindingIPImolecular_function
GO:0005622IntracellularIDAcellular_component
GO:0005634NucleusIEAcellular_component
GO:0005737CytoplasmIEAcellular_component
GO:0005783Endoplasmic reticulumTAScellular_component
GO:0005829CytosolTAScellular_component
GO:0005856CytoskeletonIEAcellular_component
GO:0006928Cellular component movementIDAbiological_process
GO:0007169Transmembrane receptor protein tyrosine kinase signaling pathwayTASbiological_process
GO:0008092Cytoskeletal protein bindingTASmolecular_function
GO:0008154Actin polymerization or depolymerizationNASbiological_process
GO:0008285Negative regulation of cell proliferationTASbiological_process
GO:0018108Peptidyl-tyrosine phosphorylationIDAbiological_process
GO:0030027LamellipodiumIDAcellular_component
GO:0030054Cell junctionIEAcellular_component
GO:0030175FilopodiumIDAcellular_component
GO:0030296Protein tyrosine kinase activator activityIEAmolecular_function
GO:0030426Growth coneIEAcellular_component
GO:0035855Megakaryocyte developmentIEAbiological_process
GO:0038096Fc-gamma receptor signaling pathway involved in phagocytosisTASbiological_process
GO:0045087Innate immune responseTASbiological_process
GO:0045202SynapseIEAcellular_component
GO:0072673Lamellipodium morphogenesisIEAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.21488251970.87877326470.89284194161.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.1170643595
GSE13712_SHEARUp0.0271778375
GSE13712_STATICUp0.1502234805
GSE19018Up0.2000122055
GSE19899_A1Up0.3074447818
GSE19899_A2Up0.0021244271
PubMed_21979375_A1Down-0.3211781215
PubMed_21979375_A2Down-0.0578160519
GSE35957Up0.1003586620
GSE36640Up0.1539951200
GSE54402Up0.3334855259
GSE9593Up0.1499511104
GSE43922Down-0.0111484030
GSE24585Up0.0945688421
GSE37065Up0.1465001146
GSE28863_A1Up0.2455368269
GSE28863_A2Up0.1267931395
GSE28863_A3Down-0.4448227768
GSE28863_A4Up0.1572104457
GSE48662Down-0.4325712174

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase
No target information from mirTarBase
  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.